Zomig Rapimelt belongs to a group of anti-migraine drugs called 5-HT1 agonists. Zomig Rapimelt is used to relieve your migraine headache and other associated symptoms of a migraine attack. Migraine headache is believed to be caused by a widening of the blood vessels in the head. Zomig Rapimelt narrows the vessels and relieves the pain and other symptoms of migraine headache. Zomig Rapimelt should not be used continuously to prevent or reduce the number of attacks you experience. Use Zomig Rapimelt only to treat an actual migraine headache attack. The usual dosage is 2.5 mg, or lower if recommended by your doctor. The Zomig Rapimelt 2.5 mg orally dispersible tablets cannot be broken in half. The dose should be taken as soon as your migraine appears, but it may be taken at any time during your migraine headache. For Zomig Rapimelt orally dispersible tablets, the blister pack should be peeled open as shown on the foil (tablets should not be pushed through the foil). The Zomig Rapimelt tablet should be placed on the tongue, where it will dissolve with the saliva. Water is not needed for the dispersible tablet. A second dose may be taken if your headache returns, but not sooner than 2 hours following the first tablet. For any attack where you have no response to the first dose, do not take a second dose without first consulting your doctor. Do not administer more than 10 mg in any 24-hour period. Before using this medication, inform your doctor if you are pregnant or planning to become pregnant, have heart or blood disease, high blood pressure, epilepsy, or liver disease.
Zomig Rapimelt is available from Canada and United Kingdom manufactured AstraZeneca. The generic also called Zolmitriptan ODT comes from Canada manufactured by Sandoz (or Teva or PharmaScience) and from United Kingdom by a different manufacturer. It is available as orally dispersible tablets of 2.5 mg in blister packs containing 6 tablets.
Stop taking Zomig and call your doctor at once if you have one of these serious side effects:
• Allergic reactions
• Fast heart rate
• Heart throbbing
• Irregular heart beat
• Sensation of chest pain, pressure or tightness, shortness of breath and sweating
• Sensation of tingling, heat, pressure or heaviness
• Shortness of breath
• Sudden or severe abdominal pain or diarrhea
• Temporary increase in blood pressure
Less serious side effects include feeling sick, vomiting, dizziness, tiredness, weakness, muscle aches and pains, difficulty swallowing, dry mouth, headache, stomach pain and increase in production of urine. Please call your doctor if you have any further concerns or questions.
Do not use Zomig Rapimelt if you are allergic to zolmitriptan, have heart disease, suffer from chest pain, severe or uncontrolled high blood pressure, are taking or have recently taken (within 24 hours) an ergotamine containing or ergot-like drug, or another triptan used to treat migraines, have a headache that is not migraine headache, are taking or have recently taken (within 2 weeks) a monoamine oxidase inhibitor (MAOI). Zomig Rapimelt Do not drive or operate heavy machinery until you are sure that you are not drowsy. Zomig Rapimelt should not be used with antidepressants, such as selective serotonin reuptake inhibitors (SSRIs), for example, fluoxetine hydrochloride, sertraline hydrochloride, fluvoxamine, serotonin norepinephrine reuptake inhibitors (SNRIs), for example, venlafaxine hydrochloride, or monoamine oxidase inhibitors (MAOIs), for example, phenelzine sulfate, tranylcypromine sulfate or moclobemide, drugs used to treat upset stomach or stomach ulcers (cimetidine), antibiotics such as ciprofloxacin.
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