Zofran Injection (Ondansetron Hydrochloride Dihydrate) is a prescription medication used to prevent nausea and vomiting caused by radiotherapy (in adults) and chemotherapy (in adults and children). The drug also prevents nausea and vomiting after surgery. The active ingredient in Zofran Injection is Ondansetron Hydrochloride Dihydrate. Ondansetron Hydrochloride Dihydrate belongs to a class of medications called serotonin 5-HT3 receptor antagonists. It works by blocking the action of serotonin, the natural substance that causes nausea and vomiting.

Manufacturer Information

Get medical help immediately if you have any signs or an allergic reaction while taking Zofran Injection. The most common side effects of Zofran may include the following:
• Constipation;
• Diarrhea;
• Drowsiness;
• Fever;
• Headache

Contact your doctor right away if you have any of the serious side effects, including:
• Blurry vision or temporary vision loss;
• Headache with severe dizziness and chest pain;
• High serotonin levels in the body, including hallucinations, agitation, fever, and loss of coordination;
• Light-headed feeling;
• Little to no urination;
• Severe constipation, bloating, or stomach pain;
• Swelling of face, tongue, or throat

These are not all of the side effects of Ondansetron Hydrochloride Dihydrate. Always contact your doctor if you notice any unusual symptoms.

You should not collect Zofran Injection if you are allergic to Ondansetron Hydrochloride Dihydrate or any ingredient in Zofran. Before you start collecting this injection, tell your doctor about your medical history, especially if you:
• Are breastfeeding or plan to breastfeed;
• Are pregnant or prepare to become pregnant;
• Have a family history of Long QT syndrome;
• Have an electrolyte imbalance;
• Have heart disease;
• Have liver disease

Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Zofran and other medicines, including anti-depressants, opioids, antibiotics, tramadol, and cancer medicines. Tell your doctor immediately if you become pregnant or think you may be pregnant. Zofran injection should only be administered in the first trimester of pregnancy if the benefits outweigh the risks. Ondansetron Hydrochloride Dihydrate taken during pregnancy may harm the unborn baby and increase the risk of having a cleft lip or palate. You should use effective contraception if you are a woman of childbearing potential. Zofran passes into breast milk. Do not breastfeed during treatment. A doctor will administer a Zofran injection. The dose will be based on your treatment. Zofran injection should start working immediately after having the injection. Contact your doctor if you continue to be sick. This drug may make you dizzy and drowsy. Do not drive or operate machines while having Zofran. Keep Ondansetron Hydrochloride Dihydrate out of reach and sight of children. Protect Zofran injection from light and not store above 300C (860F).

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