Farxiga (Dapagliflozin) is a sodium-glucose co-transporter 2 inhibitor. It is used to reduce blood sugar levels in patients with type 2 diabetes. Dapigliflozin acts in the kidneys, where it allows the excretion of excess glucose from the blood into the urine. This reduces the blood sugar level. This medication may be used alone or in combination with other antidiabetic medicines if blood glucose levels aren’t adequately controlled.
In a 2025 randomized, double-blind, multicenter trial published in the Diabetes & Metabolism Journal titled "Efficacy and Safety of Evogliptin Add-on Therapy to Dapagliflozin/Metformin Combinations," researchers assessed the impact of intensifying treatment in patients with inadequately controlled type 2 diabetes. The study demonstrated that adding a third agent to the baseline regimen of dapigliflozin and metformin significantly improved glycemic control, with a placebo-subtracted HbA1c reduction of 0.70%. Consistent with earlier findings by Matthaei et al. (2015), the triple-therapy regimen also facilitated sustained weight loss and a decrease in systolic blood pressure. Farxiga has a low risk of causing low blood sugar (hypoglycemia) when used alone. However, the risk increases significantly when it is used in combination with insulin or insulin secretagogues such as sulfonylureas.
Manufacturer Information
The brand name Farxiga is manufactured by Bristol-Myers Squibb (in partnership with AstraZeneca) and is marketed in several countries, including Canada (as Forxiga), the United Kingdom, India, and Turkey. The generic dapagliflozin is manufactured in Canada and is currently dispensed by Apotex. Both are available in 5 mg and 10 mg tablet strengths. We also offer other diabetes medications such as
Synjardy and
Jardiance.
The information below lists potential side effects and risks. It is crucial to discuss these with your doctor or pharmacist.
Common Side Effects – The following are some common side effects of Farxiga. Contact your doctor if you experience these common side effects and they are severe or bothersome.
• Back pain
• Changes in urination (including urgency or increased frequency)
• Constipation
• Dizziness
• Genital yeast infections (in both men and women)
• Nausea
• Urinary tract infections (UTIs)
Other Potential Side Effects: (less common) - These effects are reported less frequently but still have a chance to occur:
• Dehydration
• Increased cholesterol levels (LDL-C)
• Joint pain
• Low blood sugar (Hypoglycemia), primarily when used with insulin or sulfonylureas
• Pain in the extremities
• Thirst (Polydipsia)
Serious Side Effects: These are rare but potentially severe. Seek your doctor or call medical emergency services immediately if any of the following occur:
• Allergic reaction (signs include severe skin rash, hives, or swelling of the face, lips, and throat)
• Dehydration/Hypovolemia (signs include severe dizziness, fainting, or very dark urine)
• Diabetic Ketoacidosis (DKA). This is a life-threatening condition where the blood becomes too acidic. Signs include nausea, vomiting, abdominal pain, confusion, and unusual fatigue.
• Fournier’s gangrene (Necrotizing fasciitis of the perineum). This is a rare but life-threatening bacterial infection of the tissue under the skin in the genital area. Seek help for pain, tenderness, swelling, or redness in the genital/anal area along with a fever.
• Serious Urinary Tract Infections (signs include burning during urination, fever, or pelvic pain)
Take this medication exactly as prescribed by your doctor. Do not take Farxiga if you have severe kidney disease, are currently on dialysis, or are experiencing diabetic ketoacidosis, as the medication is contraindicated in these situations. It is vital to inform your healthcare provider of your complete medical history, specifically if you have a history of alcoholism, bladder infections, liver disease, polycystic kidney disease, or pancreatic issues. While on this medication, you should avoid alcohol consumption and exercise caution when moving from a sitting to a standing position to prevent dizziness or fainting. Additionally, discuss all current treatments with your physician—including insulin, diuretics, lithium, and other diabetes medications—to avoid potential drug interactions. If you are pregnant or planning to become pregnant, consult your doctor immediately, and do not breastfeed while using this medication.
Dietary and Lifestyle Factors
While Farxiga can be taken with or without food, it is essential to take it at the same time each morning to help manage your blood sugar levels effectively throughout the day. Unlike some other medications, Farxiga does not have specific restrictions regarding leafy greens or most fruits; however, you should ensure you maintain consistent hydration by drinking plenty of water, as the drug’s mechanism increases glucose and fluid excretion through the urine. You should avoid or limit alcohol consumption, as alcohol can significantly increase your risk of dehydration and a dangerous condition called ketoacidosis, even if your blood sugar levels appear normal. Additionally, it is advisable to maintain a low-sodium diet and closely monitor salt intake, as Farxiga can lower blood pressure and may cause dizziness if electrolyte balance is not maintained appropriately. For optimal results, pair your treatment with a healthy diet and regular exercise, as recent 2025 clinical perspectives emphasize that combining SGLT2 inhibitors with structured lifestyle modifications yields the most significant benefits for heart and kidney health.
Where can I buy Farxiga online?
You can buy Farxiga online from our certified Canadian Pharmacy, or by email (CustomerService@canadianpharmacyking.com), by phone (1-877-745-9217), or by fax or mail.
Do I need a prescription to buy Farxiga?
A prescription is required to purchase Farxiga from a CIPA-verified Canadian pharmacy.
Can I purchase Farxiga without a prescription?
No, you cannot purchase Farxiga without a prescription. A valid prescription is required.
How can I get a prescription for Farxiga?
You can get a prescription for Farxiga from your doctor or a qualified healthcare provider.
Are there discounts or coupons available for Farxiga?
Unfortunately, there are no discounts or coupons available for Farxiga. However, Canadian Pharmacy King is proud to offer high-quality prescription medications at affordable prices.
Does Farxiga need to be refrigerated?
Farxiga can be stored at room temperature away from heat and moisture.
Can you take Vitamin D with Farxiga?
There is no known drug interaction between Farxiga and Vitamin D. However, always inform your doctor of all supplements you are taking, as Farxiga can increase the risk of hypoglycemia when combined with other glucose-lowering medications like insulin or sulfonylureas.