Eliquis (Apixaban) is an oral factor Xa inhibitor anticoagulant used to reduce the risk of stroke and dangerous blood clots (systemic embolism) in patients with atrial fibrillation that is not caused by a heart valve problem. It is also used in people who have undergone total hip replacement or knee replacement surgery.
Building on the 2013 foundational data, more recent clinical evaluations continue to support the clinical profile of Eliquis. In a 2026 study published in The American Journal of Cardiology titled "Effectiveness and Safety of Apixaban versus Warfarin in Atrial Fibrillation Patients with Malignancy," researchers conducted a propensity-matched analysis to evaluate the drug's performance in high-risk, complex patient groups. The data indicated that apixaban is non-inferior to warfarin for preventing stroke in patients with active malignancy and is associated with a lower risk of major bleeding. However, its impact on overall survival remains comparable to other treatment options. These findings reinforce the 2013 conclusions by Budovich, Zargarova, and Nogid, confirming that Eliquis maintains a superior safety margin for bleeding risk even when administered to patients with significant comorbidities, such as active malignancy.
Manufacturer Information
We currently have the brand-name product from Bristol-Myers Squibb in Canada, India, Turkey, Australia, and the United Kingdom, and the generic Apixaban is available in India (Apigat by Natco Pharma) and in Canada (Apo-Apixaban by Apotex).
Eliquis and generic apixaban are available in 2.5 mg and 5 mg; a prescription is required to order Apixaban. Its costs vary depending on the brand, dosage, quantity, and the supplier's country of origin. Canadian Pharmacy King is an accredited online pharmacy that offers this medication at a lower cost than the average U.S. retail price. Other medications for the treatment of stroke or systemic embolism include
Pradaxa.
The information below lists potential side effects and risks. It is crucial to discuss these with your doctor or pharmacist.
Common Side Effects – The following are common side effects of Eliquis. Contact your doctor if you experience these side effects and they are severe or bothersome.
• Anemia (low red blood cell count)
• Bruising (easy or frequent)
• Nausea
• Nosebleeds (Epistaxis)
• Slight bleeding from gums (especially after brushing teeth)
Other Potential Side Effects: (less common) - These effects are reported less frequently but can still occur:
• Blood in the urine (Hematuria)
• Blood in the stool (may appear bright red or black and tarry)
• Dizziness
• Heavy menstrual periods
• Low blood pressure (Hypotension)
• Rectal bleeding
• Swelling of the joints (caused by internal bleeding)
Serious Side Effects - These are rare but potentially severe. Seek your doctor or call medical emergency services immediately if any of the following occur:
• Allergic reaction (signs include swelling of the face, lips, or tongue; difficulty breathing; or a severe, itchy skin rash)
• Internal bleeding (signs include severe headache, sudden weakness, or confusion, which may indicate a brain bleed)
• Major hemorrhage (prolonged or uncontrollable bleeding from any site)
• Spinal/Epidural hematoma (signs include tingling, numbness, or muscle weakness in the legs or back; this is a critical risk for patients undergoing spinal procedures)
• Vomiting blood (may look like coffee grounds)
Take this medication exactly as prescribed by your doctor. Do not take Eliquis if you currently have certain types of abnormal bleeding or have had a severe allergic reaction to Apixaban. It can cause bleeding, which can be serious. Patients with prosthetic heart valves or atrial fibrillation caused by a heart valve problem should not take this medication. Tell your doctor about all the medications you take, including prescription and over-the-counter medications, vitamins, and herbal supplements. Some of your other medications may affect the efficacy of Eliquis. Certain medicines may increase your risk of bleeding or stroke when taken together.
Dietary and Lifestyle Factors
While Eliquis can be taken with or without food, it is essential to take it at the same time every day to maintain a steady level of the medication in your bloodstream. Unlike older anticoagulants like warfarin, you do not need to avoid specific vegetables or leafy greens, as Eliquis does not interact with Vitamin K. Unlike some other medications, Eliquis does not have a known significant interaction with grapefruit or grapefruit juice. You can typically consume grapefruit safely while taking this medication without increasing your risk of bleeding. Additionally, it is wise to limit alcohol consumption, as alcohol can increase the risk of stomach bleeding and may increase the likelihood of falls or injuries while on blood thinners. It is critical to avoid or strictly limit the use of Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), such as ibuprofen, naproxen, and aspirin, unless specifically directed by your doctor. Taking these with Eliquis significantly increases your risk of serious internal bleeding. For the best results, maintain a consistent routine and stay hydrated, as recent 2025 clinical perspectives emphasize that medication adherence combined with moderate, safe physical activity is essential for the long-term prevention of stroke and systemic embolism.
Where can I buy Eliquis online?
You can buy Eliquis online from our certified Canadian Pharmacy, or by email (CustomerService@canadianpharmacyking.com), by phone (1-877-745-9217), or by fax or mail.
Do I need a prescription to buy Eliquis?
A prescription is required to purchase Eliquis from a CIPA-verified Canadian pharmacy.
How much does Eliquis cost?
Eliquis costs can vary depending on the brand, dosage, quality, and supplier country. At Canadian Pharmacy King, we are proud to offer highly competitive prices on Eliquis.
Does my insurance plan cover Eliquis?
Unfortunately, we do not accept any insurance for Eliquis.
Can I use a prescription discount card or coupon to save on Eliquis?
Unfortunately, there is no discount card or coupons for Eliquis. Choosing a generic version or a three-month supply can help you lower the cost of Eliquis.
Can I buy Eliquis in bulk or with a 90-day supply to save money?
Buying a 90-day supply of Eliquis can help you save on the total cost of your prescription.