Yentreve (duloxetine) contains the active ingredient duloxetine. Yentreve increases the levels of serotonin and noradrenaline in the nervous system. Yentreve is a medicine to be taken by mouth to treat Stress Urinary Incontinence (SUI) in women. Stress urinary incontinence is a medical condition in which patients have accidental loss or leakage of urine during physical exertion or activities such as laughing, coughing, sneezing, lifting, or exercise. Yentreve is believed to work by increasing the strength of the muscle that holds back urine when you laugh, sneeze, or perform physical activities. The efficacy of Yentreve is reinforced when combined with a training program called Pelvic Floor Muscle Training (PFMT). Yentreve should not be used for children and adolescents under 18 years. Yentreve is for oral use. You should swallow your capsule whole with a glass of water.
Canadian Pharmacy King currently offers the brand Yentreve from the United Kingdom by Eli Lilly in the strength of 20 mg and 40 mg hard gastro-resistant capsules. The generic alternative is unavailable.
Common side effects of Yentreve may include feeling sick (nausea); dry mouth; constipation; fatigue; lack of appetite; trouble sleeping; feeling agitated; less sex drive; anxiety; difficulty sleeping; headache; feeling sluggish; feeling sleepy; tremor; numbness; pricking or tingling of the skin; blurred eyesight; feeling of dizziness; increased blood pressure; flushing; diarrhoea, stomach pain, being sick (vomiting), heartburn or indigestion; increased sweating; weakness, shivering. Call your doctor immediately if you notice less common but more serious side effects such as:
• Allergic reactions;
• Decreased thyroid gland activity which can cause tiredness or weight gain;
• Throat inflammation that causes a hoarse voice
This is not a complete list of side effects, and others may occur. Contact your doctor if any of these side effects worsen or persist.
Do not take Yentreve if you are allergic to Duloxetine or any of the other ingredients of this medicine; have liver disease; have severe kidney disease; are taking another medicine known as a monoamine oxidase inhibitor; are taking fluvoxamine which is usually used to treat depression, ciprofloxacin or enoxacin which are used to treat some infections. Talk to your doctor if you have high blood pressure or heart disease. Talk to your doctor before you take Yentreve if you are taking medicines to treat depression; are taking St. John’s Wort; have kidney disease; have had seizures (fits); have had mania; suffer from bipolar disorder; have eye problems; have bleeding disorders; if you are pregnant; are at risk of low sodium levels; are taking other medicines containing duloxetine. Medicines like Yentreve may cause symptoms of sexual dysfunction. Please tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines, including medicines obtained without a prescription. The main ingredient of Yentreve, duloxetine, is used in other medicines for other conditions: diabetic neuropathic pain, depression, anxiety and urinary incontinence. Using more than one of these medicines at the same time should be avoided. Yentreve may be taken with or without food. You should take extra care if you drink alcohol while taking Yentreve. Yentreve may make you feel sleepy or dizzy. Do not drive or use any tools or machines until you know how Yentreve affects you. If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
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