Sibelium (Flunarizine) is a prescription medication used to prevent migraine headaches with or without aura. The drug may also be used for the symptomatic treatment of vestibular vertigo. A migraine is a neurological condition characterized by severe headaches, often accompanied by symptoms such as nausea, vomiting, and extreme sensitivity to light and sound. Vestibular vertigo is dizziness or a spinning sensation due to a diagnosed functional disorder of the vestibular system. The active ingredient in Sibelium is Flunarizine. Flunarizine belongs to a class of medications known as calcium channel blockers. It works by preventing the influx of calcium ions into cells. This action helps to stabilize the blood vessels in the brain, preventing the excessive constriction and dilation that can lead to a migraine. It also has effects that help prevent the release of certain substances that contribute to the migraine process.
Manufacturer Information
We currently offer the brand Sibelium from India, manufactured by Johnson & Johnson, in strengths of 5 mg and 10 mg tablets. The brand is also available from India, manufactured by Janssen-Cilag (a Johnson & Johnson company), in the strength of 5 mg tablets. The generic Flunarizine is also available from India by a different manufacturer in the strengths of 5 mg and 10 mg tablets.
Get medical help immediately if you have any of these signs or an allergic reaction while using Sibelium. The most common side effects of Sibelium may include the following:
• Constipation;
• Drowsiness;
• Fatigue;
• Increased appetite;
• Stomach upset;
• Weight gain
Contact your doctor right away if you have any of the severe side effects, including:
• Extrapyramidal symptoms, such as tremors, rigidity, and difficulty moving;
• New or worsening depression;
• Signs of an allergic reaction, such as trouble breathing, hives, swelling of the face, lips, or throat
These are not all of Sibelium's side effects. Always contact your doctor if you notice any unusual symptoms.
You should not use Sibelium if you are allergic to Flunarizine or any ingredient in Sibelium. Before you start using this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or planning to breastfeed;
• Are pregnant or planning to become pregnant;
• Have gastrointestinal diseases;
• Have glaucoma;
• Have heart problems;
• Have liver problems;
• Have porphyria;
• Have preexisting symptoms of Parkinson's disease or other extrapyramidal disorders;
• Have urinary tract obstruction;
• Have a history of depression
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Sibelium and other medicines, such as amlodipine, carbamazepine, phenytoin, and ethinyl estradiol. Do not take alcohol when using this medicine. Alcohol can increase the risk of dizziness or drowsiness. Tell your doctor if you are pregnant or planning to become pregnant. It is unknown if Sibelium is safe for use in pregnancy. Discuss the benefits and risks of using this medicine when pregnant with your doctor. Inform your doctor if you are breastfeeding or planning to breastfeed. It is unknown if Flunarizine is excreted in breast milk or if it may harm a nursing infant. This medicine should be used when breastfeeding only if the benefits outweigh the risks.
Use this medicine exactly as your doctor prescribes it. Sibelium is a tablet. Swallow the tablet whole with a glass of water. Do not crush, chew, or break it. You can take this drug with or without food, preferably at bedtime. Do not stop using this medicine without consulting your doctor. Stopping Sibelium abruptly can cause adverse effects. Ensure you complete the course of your treatment. It may take several weeks to see the full impact of the drug. Store this drug at room temperature, away from moisture, heat, and light. Keep out of the reach of children.