Rozlytrek (Entrectinib) is a prescription medication used to treat metastatic (lung cancer that has already spread) non-small cell lung cancer (NSCLC) that is caused by ROS1 gene. This medication is used in adults and children over the age of 12 years old, who have solid tumors that have spread and cannot be removed safely with surgery, or when other treatments have failed. Rozlytrek is used only if your cancer has a specific abnormal gene. Entrectinib belongs to a class of drugs known as kinase inhibitors. It works by interfering with the growth of cancer cells and destroys them.
We currently offer the brand Rozlytrek from Canada by Hoffman - La Roche. The generic version is not available. (Payment required before the order is processed and no cancellation is allowed).
Seek emergency medical help if you have any signs of an allergic reaction to this medication.
The common side effects of Rozlytrek may include changes in your mental status, change in sense of taste or touch, constipation, cough, diarrhea, dizziness, fever, muscle or joint pain, nausea, swelling, tiredness, trouble breathing, vision changes, vomiting, and weight gain.
Contact your doctor immediately if you have any of the serious side effects such as:
• Bone pain or movement problems;
• Changes in vision, blurred or double vision, etc.;
• Confusion, hallucinations, memory problems;
• Cough, wheezing or shortness of breath;
• Fast or pounding heartbeats, fluttering in your chest;
• Loss of appetite, nausea, vomiting;
• Swelling in your lower legs, rapid weight gain
This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.
Before taking Rozlytrek, tell your doctor if you have any allergies. Prior to taking this medication, tell your doctors about your medical history and if you have ever had:
• A nervous system disorder;
• Heart problems;
• Liver or kidney disease;
• Long QT syndrome;
• Vision problems
Rozlytrek may cause blurred vision, or make you dizzy or may impair your reactions. Avoid driving or hazardous activity until you know how this medication will affect you. Avoid the use of grapefruit products. Tell your doctor about all the medications you take including prescription, nonprescription, herbal products, and vitamins. There may be a drug interaction between Rozlytrek and other medications. Rozlytrek can harm an unborn baby or cause birth defects if the mother or the father is using this medication. Women may need to have a negative pregnancy test before starting treatment and they will have to use effective birth control to prevent pregnancy while using this medication and for at least five weeks after the last dose. Men will also need to use effective birth control if their partner is able to get pregnant while using this medication and at least three months after their last dose. Inform your doctor right away if a pregnancy occurs while either the mother or the father is using this medication. Do not breastfeed while using this medication and for at least seven days after the last dose.
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