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Home | Prescription Drugs | Renagel

Renagel (Sevelamer)

Type
Drug
Mfr.
Country
Dosage
Qty
Price(USD)
Type:
Drug:Renagel
Mfr.:Genzyme
Country:Canada
Dosage:800 mg
Qty:180
Price:$427.99
Type:
Sevelamer
Generic
India
400 mg
50
$94.99
Type:
Drug:Sevelamer
Mfr.:Generic
Country:India
Dosage:800 mg
Qty:60
Price:$117.99

Information

Renagel (Sevelamer) is indicated for the control of serum phosphorus in patients with chronic kidney disease (CKD) on hemodialysis. Renagel (Sevelamer) is contraindicated in patients with hypophosphatemia or bowel obstruction In a 52-week study, the most common side effects included vomiting, nausea, diarrhea, and dyspepsia. Drug-drug interactions may occur with some medications and should be taken into consideration when instructing patients how to take Renagel (Sevelamer).

Renagel's mechanism of action is to bind phosphate in the gastrointestinal tract and prevent phosphate from being absorbed. Chemically, Renagel (Sevelamer) is a polyamine - a polymer that is loaded with amines. The purpose of the high density of amine groups on the polymer is to provide a large number of positive charges. The positive charges then interact with the very negatively charged phosphate anions, and thus, the phosphate anions are strongly bound to the polymer cations.

Side Effects

Common side effects of Renagel include dyspepsia, peritonitis, diarrhea, nausea, constipation, pruritus, abdominal distension, vomiting, fatigue, anorexia and arthralgia.

The generic alternative is not manufactured by the company that makes the brand product.

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