This product belongs to the class of medications known as estrogen replacement therapy. It is used to treat the vaginal symptoms of menopause, such as dryness, burning, irritation, and painful sexual intercourse. This medication contains a mixture of estrogen hormones. Estrogen is a female sex hormone produced by the ovaries. Most postmenopausal women may experience postmenopausal vulvar and vaginal atrophy (VVA, or atrophic vaginitis), which is thinning, drying, and inflammation of the vaginal walls that may occur when your body has less estrogen. The dose of this medication is individualized for the person using the cream. The lowest dose that will treat the symptoms should be used.
Manufacturer Information
We currently have the brand-name product from Wyeth in India and from Pfizer in Canada. Premarin is available as a cream in strengths of 14 g and 30 g.
The generic version is currently not available at this pharmacy.
The information below lists potential side effects and risks. It is crucial to discuss these with your doctor or pharmacist.
Common Side Effects – The following are common side effects. Contact your doctor if you experience these side effects and they are severe or bothersome.
• Abdominal cramps or bloating
• Breast tenderness or enlargement
• Headache
• Nausea and vomiting
• Vaginal itching or burning
• Vaginal yeast infection (candidiasis)
Other Potential Side Effects: (less common) – These effects are reported less frequently but can still occur:
• Changes in libido (sex drive)
• Dizziness
• Fluid retention or swelling (edema)
• Hair loss (alopecia)
• Irregular vaginal bleeding or spotting
• Skin rash or discoloration
Serious Side Effects - These are rare but potentially severe. Seek your doctor or call medical emergency services immediately if any of the following occur:
• Cardiovascular Events
• Endometrial Neoplasia
• Gallbladder Disease
• Hypercalcemia
• Liver Dysfunction
• Severe Allergic Reaction
• Vision Changes
This treatment should not be used to prevent heart disease, heart attacks, strokes, or dementia. Clinical evidence suggests that estrogen therapy may increase the risk of these serious conditions, as well as the risk of invasive breast cancer and blood clots in the legs or lungs. To minimize these risks, it should be used at the lowest effective dose for the shortest duration consistent with treatment goals.
This medication can harm an unborn baby or cause congenital disabilities and must not be used during pregnancy. If you become pregnant or suspect you are pregnant while using this cream, notify your healthcare provider immediately.
Additionally, conjugated estrogens may reduce breast milk production and can be excreted into breast milk. Therefore, it is generally advised not to use this medication while breastfeeding.
Premarin Vaginal cream is not indicated for pediatric use and should not be administered to anyone under 18 years of age without specific medical advice and supervision.
There are several important drug interactions to consider, as conjugated estrogens can alter how your body responds to other treatments. This medication may interact with antidiabetic medications and blood-pressure-lowering drugs, potentially requiring dosage adjustments for those conditions. Interactions may also occur with certain antibiotics and antifungals, such as clarithromycin, itraconazole, and ketoconazole, as well as with other medications, including cyclosporine, dexamethasone, morphine, topiramate, and warfarin.
To ensure patient safety, always provide your doctor and pharmacist with a comprehensive list of all prescription, over-the-counter, and herbal supplements you are taking.
How do I order?
You can order this medication from our website, by email (CustomerService@canadianpharmacyking.com), by phone (1-877-745-9217), or by fax or mail.
Is a prescription required?
Yes, a prescription is required when purchasing this medication.
Can I get a prescription in the USA and use it to buy medication from Canada?
Yes, you can get a prescription from your physician in the USA and use it to buy from a Canadian pharmacy.
Are there any discounts or coupons available?
Unfortunately, no discounts or coupons are available. However, we are proud to offer high-quality prescription medications at affordable prices.
Can I have this medication shipped from Canada to my address in the USA?
Yes, you can get this medication shipped to your address (or home) in the USA from Canada.
What are the shipping costs and delivery times from Canada to the USA?
It may take 4-8 business days for your order to ship from Canada, and our shipping cost to the area is $10.00. If you have any questions about the shipping frame, please get in touch with our customer support at 1-877-745-9217 for details.
How can I tell if an online pharmacy is legitimate?
Any CIPA-certified pharmacy is licensed, reputable, and must follow strict safety protocols. CanadianPharmacyKing.com is verified by the Canadian International Pharmacy Association (CIPA).