Premarin (Conjugated Estrogens) belong to the class of medications known as estrogen replacement therapy. Estrogen is a female sex hormone produced by the ovaries. Once a woman reaches menopause, the ovaries produce less estrogen and symptoms of menopause can occur. Conjugated estrogen is an estrogen replacement hormone used to manage menopausal symptoms such as abnormal uterine bleeding (spotting), hot flashes, sweating, and chills. This medication may also help in the treatment and preventions of osteoporosis caused by estrogen deficiency when combined with diet, calcium and exercise. It is sometimes used as part of cancer treatment in women and men. The recommended dose of this medication ranges from 0.3mg to 1.25mg daily, depending on the condition being treated. It is recommended that this medication be taken at the lowest dose possible and for the shortest duration required to treat the condition.
We currently have the brand from Canada (by Pfizer), UK, New Zealand, United States, India (by Wyeth). Premarin is available in tablet form and strengths in 0.3 mg, 0.625 mg, and 1.25 mg. Generic Conjugated Estrogens 0.625 mg on back order!
Premarin Side Effects
Contact your doctor immediately if you experience these side effects:
• A breast lump;
• Abnormal vaginal bleeding;
• Chest pain or heavy feeling;
• Confusion, problems with memory or concentration;
• Jaundice (yellowing of the skin or eyes);
• Migraine headache;
• Pain, swelling, warmth, or redness in one or both legs;
• Pain, swelling or tenderness in your stomach;
• Sudden numbness or weakness, especially on one side of the body;
• Sudden severe headache, confusion, problems with vision, speech, or balance;
• Swelling in your hands, ankles, or feet
Less serious side effects may include:
• Breast pain, tenderness, or swelling;
• Changes in weight or appetite;
• Changes in your menstrual periods, decreased sex drive;
• Freckles or darkening of facial skin;
• Mild headache, nervousness, dizziness, tired feeling;
• Mild nausea, vomiting, bloating, stomach cramps;
• Problems with contact lenses;
• Vaginal itching or discharge
Premarin should not be used to prevent heart disease or dementia, because this medicine may actually increase your risk of developing these conditions. Long term use of Premarin may increase your risk of breast cancer, heart attack, stroke or blood clot. Talk to your doctor about your risks before using the medication. This medication should not be used during pregnancy. If you become pregnant while taking this medication, contact your doctor immediately. This medication passes into breast milk and is not recommended for breast-feeding women. There may be an interaction between Premarin and other medications such as anastrazole, ascorbic acid (vitamin C), blood pressure lowering agents, cyclosporine, ropinirole, topiramate, warfarin, thyroid medications, etc. Please consult with your doctor if you are taking any of these medications.
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