Praluent (Alirocumab subcutaneous injection) is an innovative cholesterol-lowering medication used to lower LDL (bad cholesterol) with heterozygous familial hypercholesterolemia (HeFH, an inherited type of high cholesterol). It is also used to treat heart disease with plaque build-up in the arteries (atherosclerosis cardiovascular disease, or CVD sometimes called hardening of the arteries). Alirocumab is a PCSK9 (Proprotein Convertase Subtilisin/Kexin Type 9) or human monoclonal antibody works by reducing the bad cholesterols in the liver. Praluent should be used along with diet and statins or other lipid lowering therapies (e.g., ezetimibe). It should be injected once every 2 weeks. Follow the instructions carefully.
We now supply the brand Praluent comes from the Canada manufactured by Sanofi Aventis. Praluent comes as a Single Use Prefilled Pen Injection (autoinjector) in pack of 2 pens. It comes in 2 dosage strengths, 75 mg/mL (recommended starting dose) and 150 mg/mL (maximum dosage). There is currently no generic equivalent for Praluent.
Store unused Praluent injection pens in the refrigerator between 36°F to 46°F (2°C to 8°C). Praluent should be stored at a room temperature for 30-40 minutes before use.
Praluent Side Effects
The most common side effects of Praluent include:
• Cold or flu symptoms such as sneezing, stuffing nose;
• injection site reactions including Itching, redness, pain;
• Sore throat;
If you suffer any serious side effects as below, please notify your doctor or pharmacist immediately.
• Difficult breathing;
• Muscle pain or stiffness;
• Urinating problems;
• Severe allergic symptoms including itching, rash, redness, or swelling of the face or throat;
Do not take Praluent if you are allergic to Alirocumab or any ingredients in this medication. Tell your doctor about all the medical conditions you have had before.
• Any allergies;
• Kidney or liver disease;
Praluent is not approved to treat patients under age 18. Tell your doctor about all the medicines you are taking including prescriptions and over-the-counter medicines including herbal supplements. Consult your doctor if you are pregnant or breastfeeding.
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