Orilissa is used to treat painful symptoms of endometriosis (when the tissue that forms the lining of the uterus grows in other parts of the body). Orilissa improves the symptoms of endometriosis after one month of taking it. It improves symptoms such as pain during periods, pain between periods, heavy bleeding during periods, pain during sex, pain or discomfort in the belly or pelvic region. Orilissa may help you feel better by reducing your pain. It may also improve emotional well-being and helps to get a control over the symptoms. This medication improves endometriosis by lowering the amount of estrogen (responsible for thickening of tissues lining the uterus) in your body. The safety and efficacy of Orilissa are not known in children under 18 years old.
The brand Orilissa is manufactured by Abbvie Inc. and comes from Canada. It may come from other international countries. It is available in the dosage form of 150 mg.
Orilissa Side Effects
Stop taking Orilissa and call your doctor at once if you have one of these serious side effects:
• Anxiety, depression, irritability, mood swings
• Liver disorder (yellowing of the skin or eyes, dark urine, abdominal pain, nausea, vomiting, loss of appetite)
Less serious side effects include hot flashes, night sweats, headache, dizziness, nausea, diarrhea, stomach pain, constipation, difficulty sleeping, decreased sex drive, stuffy nose, sore throat, sinus infection, common cold, menstrual bleeding changes such as irregular bleeding or spotting, increase or decrease in bleeding, or no bleeding at all and abnormal blood test results.
This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.
Take Orilissa at about the same time each day, even if symptom-free. You may take Orilissa with or without food. You should start taking Orilissa on the day you start your period to ensure you are not pregnant. You must confirm that you are not pregnant before starting treatment with Orilissa. The dose prescribed by the doctor can be either 150 mg once a day or 150 mg twice a day depending on your symptoms. Do not use the medication if you are allergic to Elagolix or any other ingredients in the medication, are pregnant or planning to become pregnant, have severe liver disease, have osteoporosis, have unexplained bleeding form vagina, are taking cyclosporine, used to prevent organ rejection. Orilissa may interact with medications such as digoxin, rifampin, midazolam, rosuvastatin, ormonal birth control that contains estrogen, such as “the pill”. Before taking Orilissa, inform your doctor if you have a history of bone mineral loss. Orilissa may result in small loss of minerals from bones. The bone mineral loss can be increased during treatment with Orilissa if you use alcohol excessively, smoke, have a history of osteoporosis, take steroids, have liver problems, have a history of mental health problems such as depression or suicidal thoughts.