Lorbrena (Lorlatinib) is a prescription medication used to treat people with non-small cell lung cancer (NSCLC) that is caused by abnormal anaplastic lymphoma kinase (ALK) gene and that has spread to other parts of your body and in patients who have taken alectinib or certinib or who have taken both the medications crizotinib and at least one other medication to treat NSCLC that is caused by ALK gene and their NSCLC is no longer responding to these treatments. Lorlatinib belongs to the class of medications called kinase inhibitors. It works by slowing or stopping the growth of cancer cells.
We currently offer the brand Lorbrena from Canada manufactured by Pfizer in the strength of 25 mg and 100 mg tablets. The generic version is not available.
The most common side effects of Lorbrena may include:
• Changes in mood, feeling sad or anxious or confused;
• Difficulty breathing or thinking;
• Numbness and tingling feeling in your joints or arms and legs;
• Pain in your joints;
• Swelling in your arms, legs, hands and feet;
• Weight gain
Contact your doctor right away if you have any of the serious side effects including:
• Brain function problems;
• Heart and lung problems;
• Increase in the cholesterol and triglyceride levels in your blood
You should not take Lorbrena if you are allergic to Lorlatinib or if you have taken certain medications called strong CYP3A inducers. Before you start taking this medication, tell your doctor about your medical history especially if you:
• Are breastfeeding or plan to breastfeed;
• Are pregnant or plan to become pregnant;
• Have had episodes of depression or seizures;
• Have high levels of cholesterol or triglycerides in your blood;
• Have problems with your heartbeat;
• Have lung or breathing problems
Tell your doctor right away if you become pregnant or think you may be pregnant. Women should use effective non-hormonal birth control during treatment with Lorbrena and for at least six months after the final dose. Men who have female partners who can become pregnant should use effective birth control during treatment and for at least three months after the final dose. Do not breastfeed during treatment with Lorbrena and for 7 days after the final dose. Lorbrena may cause decreased fertility in men which could affect their ability to father a child. This medication may you dizzy or cause vision changes. Alcohol and marijuana can make you dizzier. You should not drive, use machinery or do any activity that requires you to be alert until you can do it safely. Limit alcoholic beverages. Tell your doctor about all the medications you take including prescription, OTC, herbal supplements, and vitamins. There may be a drug interaction between Lorlatinib and other medications. It is unknown if Lorbrena is safe and effective in children.
Check out our latest Blog Post
Canada's New International Travel Restrictions Complicate Access to Prescription Medications
The content on this page has been supplied to canadianpharmacyking by an independent third party contracted to provide information for our website. canadianpharmacyking relies on these third parties to create and maintain this information and cannot guarantee the medical efficacy, accuracy or reliability of the information that has been provided to us. If you require any advice or information about the drugs on this page, a medical condition or treatment advice, you should always speak to a health professional. Please note that not all products, including any referenced in this page, are shipped by our affiliated Canadian Pharmacy. We affiliate with other dispensaries that ship product to our customers from the following jurisdictions: Canada, New Zealand, Australia, Turkey, Mauritius, India, and the United Kingdom.
The items in your order maybe shipped from any of the above jurisdictions. The products are sourced from various countries as well as those listed above. Rest assured, we only affiliate with licensed pharmacies and fulfillment centers that procure products from reliable sources.