Lokelma (Sodium Zirconium Cyclosilicate)
Lokelma (Sodium Zirconium Cyclosilicate) is used to treat high levels of potassium in the blood (hyperkalemia) in adults. Lokelma belongs to a group of drugs called potassium binders. This medication works by increasing potassium excretion through binding of potassium in the gastrointestinal tract which in turn lowers blood potassium levels. The symptoms of high levels of potassium are nausea, muscle weakness or tiredness, irregular heartbeats and paralysis. The recommended dose for initial treatment of hyperkalemia is 10 gm administered three times a day for up to 48 hours.
Canadian Pharmacy King currently offers the brand Lokelma sachets from Canada by AstraZeneca. It is available in the strength of 5 gm and 10 gm sachets which comes in one pack of 30 sachets. There is no generic available for this medication.
The common side effects of Lokelma may include:
• Excess fluid in the lungs or swelling of hands, feet, arms or legs;
• Low blood potassium
Many people using this medication do not have any serious side effects. Talk to your doctor if you have any further concerns or questions.
You should not take Lokelma if you are allergic to Sodium Zirconium Cyclosilicate or if you have any other allergies. Before you start taking this medication, talk to your doctor about your medical history especially of stomach or intestinal problems, conditions affected by the salt in this medication and kidney problems because this medication contains salt. Lokelma does not work right away and should not be used to treat life-threatening high levels of potassium. Inform your doctor if you are pregnant before using this medication. Lokelma is unlikely to pass into breast milk. Talk to your doctor before breast-feeding.
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