Take Loestrin exactly as prescribed by your doctor. Decide with your doctor or clinic what is the best day for you to start taking your first pack of pills. Your pills may be either a 21-day or 28-day type. With 21-day type, you are 21 days on pills with seven days off pills. You must not be off the pills for more than seven days in a row. With 28-day type, you take 21 pills, which contain hormones and seven pills, which contain no hormones. Do not take Loestrin if you are have unusual vaginal bleeding that has not yet been diagnosed, have blood clots in the legs, lungs, eyes or elsewhere, have or had a stroke, heart attack or chest pain (angina pectoris), have known or suspected cancer of the breast or sex organs, liver tumor associated with the use of the pill or other estrogen-containing products, jaundice or liver disease, are pregnant or suspected to be pregnant. Loestrin may interact with, medications such as rifampin (anti-tuberculosis medication), anticonvulsants such as phenobarbital, phenytoin, carbamazepine, troglitazone (an anti-diabetic), antibiotics such as ampicillin, tetracycline, and griseofulvin, atorvastatin (cholesterol-lowering drug), ascorbic acid, acetaminophen, prednisolone (a corticosteroid), theophylline (used to treat asthma), cyclosporine (used to prevent organ rejection after transplant).
Before taking Loestrin, inform your doctor have breast conditions, a strong history of breast cancer, breast disorders including pain, discharge from the nipples, thickenings, or lumps, diabetes, high blood pressure, abnormal levels of fats in the bloodstream (high cholesterol or triglycerides), smoke cigarette, suffer from migraine headaches, have a heart or kidney disease, epilepsy, mental depression, fibroid tumors of the uterus, gallbladder or pancreatic disease, have any plans for forthcoming surgery, have a history of jaundice or other liver disease, have a family history of blood clots, heart attacks or strokes.