This medication is a phosphodiesterase inhibitor used to treat erectile dysfunction (male impotence). It works by relaxing muscles and increasing blood flow to the penis during sexual stimulation. This helps men achieve and maintain an erection. It only works with sexual stimulation and does not increase sexual desire. The recommended starting dose is 10 mg, taken approximately 60 minutes before sexual activity. However, some men may experience results as early as 25 to 30 minutes after ingestion.
A systematic review and meta-analysis published in 2021 (Ji et al.) reaffirmed the clinical efficacy and safety of vardenafil (Levitra) for treating erectile dysfunction across a diverse patient population. The study, which combined data from 14 randomized controlled trials, concluded that vardenafil significantly improves erectile function scores, including the International Index of Erectile Function (IIEF-EF) and successful penetration rates (SEP2/SEP3), compared to placebo. Additionally, the analysis emphasized that vardenafil is generally well tolerated, with a safety profile characterized by transient, mild-to-moderate side effects, reinforcing its role as a reliable, potent, and highly selective PDE5 inhibitor for both initial and long-term ED management.
Manufacturer Information
We currently have the brand-name product by Bayer from Turkey and the United Kingdom.
Centurion makes the generic vardenafil Filtra, while Ajantha produces Valif. It may also come from other suppliers worldwide. Other known names include Savitra (by Sava Medica) and Vilitra (by Centurion).
Levitra is available as tablets and dispersible (sublingual) tablets, with three strengths: 5 mg, 10 mg, and 20 mg.
The information below lists potential side effects and risks. It is crucial to discuss these with your doctor or pharmacist.
Common Side Effects – The following are common side effects. Contact your doctor if you experience these side effects and they are severe or bothersome.
• Dizziness
• Flushing (warmth or redness in the face/neck)
• Headache
• Indigestion (Dyspepsia)
• Nasal congestion (Stuffy nose)
• Nausea
• Runny nose (Rhinitis)
Other Potential Side Effects: (less common) – These effects are reported less frequently but can still occur:
• Abdominal pain
• Back pain
• Blurred vision
• Changes in color vision (e.g., seeing a blue tinge)
• Drowsiness
• Muscle aches (Myalgia)
• Sensitivity to light (Photosensitivity)
• Watery eyes
Serious Side Effects - These are rare but potentially severe. Seek your doctor or call medical emergency services immediately if any of the following occur:
• Cardiovascular Events: Chest pain, irregular heartbeat (arrhythmia), or shortness of breath.
• Hearing Loss: Sudden decrease or loss of hearing, sometimes accompanied by ringing in the ears (tinnitus).
• Hypotension: A sudden drop in blood pressure, which may lead to fainting or severe dizziness.
• Priapism: A painful or prolonged erection lasting longer than 4 hours; this requires immediate medical attention to prevent permanent tissue damage.
• Vision Loss: Sudden loss of vision in one or both eyes, which may be a sign of Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION).
The primary clinical concern with Levitra (vardenafil) is its potential to cause a sudden, life-threatening drop in blood pressure when combined with certain vasodilators. This is particularly important for patients with underlying cardiovascular disease, as it may lead to syncope, myocardial infarction, or stroke. Additionally, vardenafil is linked to a risk of Priapism—a prolonged, painful erection lasting over four hours—which requires emergency medical treatment to prevent permanent tissue damage. Rare cases of sudden vision or hearing loss have also been reported, potentially indicating Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) or other vascular issues.
Pharmacologically, Levitra is primarily metabolized via hepatic CYP3A4. Using it alongside Strong CYP3A4 Inhibitors, such as certain antivirals or antifungals, can cause dangerously high plasma levels of the medication.
Furthermore, taking Levitra with Alpha-Blockers (used for hypertension or BPH) increases the risk of symptomatic hypotension because of the combined vasodilatory effects.
Dietary and Lifestyle Factors
To ensure the safety and effectiveness of your treatment, certain routine adjustments are necessary. For the quickest onset of action, it's best to take this medication on an empty stomach or after a light meal. Eating vardenafil with a high-fat meal (such as fried foods or burgers) can noticeably delay intestinal absorption and lower its peak blood level. If you're currently taking alpha-blockers or have a history of heart disease, monitor your blood pressure closely to reduce the risk of dizziness.
While moderate alcohol consumption typically does not cause a dangerous drop in blood pressure when taken with Levitra, it is best to limit alcohol intake as it can impair your ability to get an erection and reduce the medication's effectiveness. You should also avoid grapefruit juice, which blocks the CYP3A4 enzyme and can cause dangerously high drug levels. Finally, since this medication may cause dizziness or temporary visual changes, such as a blue-green tint, avoid driving or operating heavy machinery until you're sure it does not affect your alertness or vision.
How do I order?
You can order this medication from our website, or by email (CustomerService@canadianpharmacyking.com), by phone (1-877-745-9217), or by fax or mail.
Is a prescription required?
Yes, a prescription is required when purchasing this medication.
Can I get a prescription in the USA and use it to buy medication from Canada?
Yes, you can get a prescription from your physician in the USA and use it to buy from a Canadian pharmacy.
Are there any discounts or coupons available?
Unfortunately, no discounts or coupons are available. However, we are proud to offer high-quality prescription medications at affordable prices.
Can I have this medication shipped from Canada to my address in the USA?
Yes, you can get this medication shipped to your address (or home) in the USA from Canada.
What are the shipping costs and delivery times from Canada to the USA?
The shipping cost to the area is $10.00. Delivery times depend on your location. Please check our
shipping information for estimated timelines.
How can I tell if an online pharmacy is legitimate?
Any CIPA-certified pharmacy is licensed, reputable, and must follow strict safety protocols. CanadianPharmacyKing.com is verified by the Canadian International Pharmacy Association (CIPA).