Inspra (Eplerenone) is used alone or in combination with other medications to treat high blood pressure, as well as to help with heart function and heart failure after a heart attack. Inspra works by blocking a chemical called aldosterone in your body. Aldosterone is a mineralocorticoid that increases blood pressure by inducing sodium and water retention. Inspra lowers levels of Aldosterone, which in turn lowers the amount of sodium and water that the body retains. Lowering high blood pressure helps to prevent strokes, heart attacks, and kidney problems.
Inspra is available from Canada by Upjohn and United Kingdom by Pfizer. The generic Eplerenone comes from India also called Eptus by Glenmark. The brand Inspra and the generic Eplerenone are both available in dosages of 25 mg and 50 mg tablets.
Common side effects of Inspra include high potassium (hyperkalemia), headache, or dizziness. Contact your doctor if you notice more serious side effects such as light-headedness, diarrhea or vomiting, little or no urination, fast or irregular heartbeats, trouble breathing, swelling in your feet or lower legs, or signs of extremely high potassium (nausea, weakness, tingly feeling, chest pain, irregular heartbeats, loss of movement).This is not a complete list of side effects and others may occur. Contact your doctor for advice on other side effects.
You should not use Inspra if you are allergic to eplerenone, or if you have high potassium levels in your blood (hyperkalemia), severe kidney disease, or type 2 diabetes with increased levels of albumin. To make sure Inspra is safe for you, tell your doctor if you have ever had kidney disease, diabetes, liver disease, high cholesterol or triglycerides, or if you take other heart or blood pressure medications. As well, tell your doctor if you are pregnant or breastfeeding in order to discuss any possible risks. Do not take potassium supplements or salt substitutes while using Inspra, unless your doctor has told you to.
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