Heptral (Ademetionine) is a prescription medication used to treat intrahepatic cholestasis in pregnant women. Cholestasis is a liver problem that occurs when the flow of bile from the liver is reduced or blocked. Heptral is also used in combination with other medicines to treat medical conditions, including depression, cystic fibrosis, and osteoarthritis. The drug also improves symptoms in people with fibromyalgia. It treats nerve problems in people with AIDS or sexual dysfunction in men with depression. The active ingredient in Heptral is Ademetionine. Ademetionine belongs to a class of drugs called nutritional supplements. Ademetionine is a naturally occurring substance in cells, tissues, and body fluids. It works by ensuring sufficient levels of glutathione in the liver are maintained to minimize liver damage. It also affects serotonin levels to regulate mood and treat depression.
Manufacturer Information
We currently offer the brand Heptral from India manufactured by Abbott in the strength of 400 mg tablets. The generic Ademetionine is not available.
Get medical help immediately if you have any of these signs or an allergic reaction while taking Heptral. The most common side effects of Heptral may include the following:
• Abdominal pain;
• Diarrhea;
• Dizziness;
• Irritability;
• Nausea
Contact your doctor right away if you have any of the severe side effects, including:
• Signs of an allergic reaction, including rashes, itchy skin, swelling of the face, lips, or throat
These are not all of the side effects of Heptral. Always contact your doctor if you notice any unusual symptoms.
You should not take Heptral if you are allergic to Ademetionine or any ingredient in Heptral. Before you start using this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or planning to breastfeed;
• Are pregnant or planning to be pregnant;
• Have a history of bipolar disorder;
• Have diabetes;
• Have glaucoma;
• Have heart disease;
• Have kidney problems;
• Have seizure disorders;
• Have thyroid problems
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Heptral and monoamine oxidase inhibitors (drugs used to treat depression), antidepressants, painkillers, etc. Avoid multivitamin medicines containing folic acid, vitamin B12, or vitamin B6 with Heptral. Tell your doctor if you are pregnant or planning to become pregnant. It is unknown if Heptral may harm an unborn baby. Inform your doctor if you are breastfeeding or planning to breastfeed. Ademetionine should only be used when breastfeeding if the benefits outweigh the potential risks to the infant. Take Heptral precisely as prescribed by your doctor. Swallow the Heptral tablet whole with water. Do not crush, chew, or break the tablet. Take this drug on an empty stomach for better absorption. Heptral may cause dizziness. Do not drive or operate machines that require alertness while taking this drug. Avoid drinking alcohol when using this drug. Alcohol may increase the side effects of Heptral. Keep this drug out of sight and reach of children. Store at room temperature, away from light and moisture.