Hadlima (Adalimumab) is a prescription medication used to reduce signs and symptoms of moderate to severe arthritis in adults, moderate to severe polyarticular juvenile idiopathic arthritis in children aged at least 2 years, and psoriatic arthritis in adults. The drug is also used to reduce the symptoms of ankylosing spondylitis in adults and moderate to severe hidradenitis suppurativa (HS) in adults. Hadlima is also used to treat severe Crohn's disease in children at least 6 years old and moderate to severe ulcerative colitis in adults. The drug is also used for other conditions like severe chronic plaque psoriasis and non-infectious intermediate, posterior, and panuveitis in adults. The active ingredient in Hadlima is Adalimumab. Adalimumab belongs to a class of medications known as tumor necrosis factor (TNF) inhibitors. It works by blocking the action of TNF, a substance in the body that causes inflammation.
Manufacturer Information
We currently offer the brand Hadlima from Canada (local pick up only), manufactured by Organon, in the strengths of 40 mg/0.8 ml and 40 mg/0.4 ml, as prefilled syringes and auto-injectors. The generic Adalimumab is currently unavailable (at this pharmacy).
Get medical help immediately if you have any of these signs or an allergic reaction while using Hadlima. The most common side effects of Hadlima may include the following:
• Cough;
• Diarrhea;
• Muscle aches;
• Shortness of breath;
• Weight loss
Contact your doctor right away if you have any of the severe side effects, including:
• Signs of a serious infection, such as severe cough, persistent fever, shortness of breath, unusual fatigue, weight loss, or loss of body fat and muscle;
• Signs of an allergic reaction, such as trouble breathing, hives, swelling of the face, lips, or throat;
• Signs of heart failure, such as swelling of your ankles or feet, sudden weight gain, and shortness of breath;
• Signs of nervous system problems, such as vision problems, weakness in your arms or legs, dizziness, numbness or tingling
These are not all of Hadlima's side effects. Always contact your doctor if you notice any unusual symptoms.
You should not use Hadlima if you are allergic to Adalimumab or any ingredient in Hadlima. Before you start using this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or planning to breastfeed;
• Are pregnant or planning to become pregnant;
• Have a nervous system disease, such as multiple sclerosis or Guillain-Barre syndrome;
• Have a planned surgery;
• Have an allergy to latex rubber;
• Have any infection;
• Have diabetes;
• Have or had heart failure;
• Have or have had cancer, especially lymphoma or skin cancer;
• Have or have had hepatitis B;
• Have recently received or are scheduled to receive a vaccine;
• Have tuberculosis or have been in close contact with someone with tuberculosis
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Hadlima and other medicines, such as abatacept, anakinra, infliximab, azathioprine, mercaptopurine, etc. Tell your doctor if you are pregnant or planning to become pregnant. It is unknown if this drug will harm an unborn baby. Discuss the potential risks of using this medicine when pregnant with your doctor. Inform your doctor if you are breastfeeding or planning to breastfeed. It may not be safe to breastfeed when using Adalimumab. Discuss the benefits and risks of using this medicine when breastfeeding with your doctor.
Use this medicine exactly as your doctor prescribes it. Hadlima is an injection. This medicine is injected subcutaneously (under the skin) using an auto-injector or prefilled syringe. Your doctor will show you how to administer this injection properly. Prepare the injection only when you are ready to administer it. Leave the injection at room temperature for 15 to 30 minutes to allow it to warm up. Do not warm the prefilled syringe using heat sources such as hot water or a microwave. Discard any of the medication that has become frozen. You may inject Hadlima into the front of your thighs and your abdomen except for 5 cm or 2 inches around your belly button (navel). Always rotate the injection site within the chosen area to prevent skin problems and ensure proper absorption. Do not use the same injection site twice in a row. Do not inject into skin that is red, hard, tender, damaged, bruised, or scarred, and do not inject through your clothes. Adalimumab affects your immune system and may increase your susceptibility to infections. Avoid contact with people who are ill or have infections. Your doctor will examine you regularly to check for infections. Store this drug in its original carton in a refrigerator. Avoid extreme heat or cold. Keep out of the reach of children.