Elelyso (Taligluceraser Alfa) is a prescription medication used to treat adults with Type 1 Gaucher disease and children with Type 3 Gaucher disease. Gaucher disease is a rare genetic condition where the protein responsible for breaking down certain cell waste products is absent or not as active as it needs to be. The active ingredient in Elelyso is Taligluceraser Alfa. Taligluceraser Alfa belongs to a class of medications called enzyme replacement therapies. It replaces the enzyme glucocerebrosidase, a protein normally found in the body responsible for breaking down certain fatty substances. This helps the body recycle wastes normally, preventing spleen, liver, bone, and blood problems caused by Gaucher disease.
Manufacturer Information
The brand Elelyso comes from Canada manufactured by Pfizer (currently unavailable). The generic Taligluceraser Alfa is not available.
Get medical help immediately if you have any of these signs or an allergic reaction while using Elelyso. The most common side effects of Elelyso may include the following:
• Dizziness;
• Headache;
• Nausea;
• Pain in your arms or legs;
• Rash
Contact your doctor right away if you have any of the severe side effects, including:
• Chest tightness;
• Flushing;
• Signs of an allergic reaction, such as trouble breathing, hives, swelling of the face, lips, or throat;
• Skin rash
These are not all of the side effects of Elelyso. Always contact your doctor if you notice any unusual symptoms.
You should not receive Elelyso if you are allergic to Taligluceraser Alfa or any ingredient in Elelyso. Before you start receiving this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or planning to breastfeed;
• Are pregnant or planning to become pregnant
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Elelyso and other medicines. Tell your doctor if you are pregnant or planning to become pregnant. It is unknown if Elelyso will harm an unborn baby. However, uncontrolled Type 1 Gaucher disease during pregnancy may cause new or worsening symptoms in the mother or complications in the baby. Inform your doctor if you are breastfeeding or planning to breastfeed. It is unknown if Taligluceraser Alfa passes into breast milk or if it may harm your nursing infant. It may not be safe to breastfeed while using Elelyso. Use this medicine exactly as your doctor prescribes. Elelyso is a vial for injection. This medication is given slowly over 1 to 2 hours into your vein, as directed by your doctor, every two weeks. If you are using this medication at home, learn all the preparation and usage instructions from your doctor. Elelyso is not a cure for Gaucher disease. Use this medication regularly to get the most benefit. Your doctor may occasionally change your dose to ensure you get the best results. Store the unmixed vial in the refrigerator, away from light and moisture. Do not freeze. Keep out of the reach of children.