Dexilant (Dexlansoprazole) is used to treat certain stomach and esophagitis problems, such as acid reflux. Dexlansoprazole delayed-release capsules belong to the class of drugs known as proton pump inhibitors (PPIs). This medication works by decreasing the amount of acid your stomach produces. Dexilant relieves symptoms such as heartburn, difficulty swallowing, and persistent cough.
This 2024 meta-analysis, “The Effect of Dexlansoprazole on Gastroesophageal Reflux Disease: A Systematic Review and Meta-Analysis,” confirms that dexlansoprazole is highly effective at resolving heartburn and reflux symptoms in patients with GERD, particularly for those with moderate to severe symptoms. Its unique Dual Delayed Release (DDR) technology allows for a second release of medication several hours after the first, providing extended relief.
Manufacturer Information
We currently offer the brand-name product from Takeda in Canada. Generic dexlansoprazole utilizing DDR technology is manufactured by Alembic Pharma (marketed as Deltone) and MSN Laboratories.
Dexilant and generic dexlansoprazole are available in 30 mg and 60 mg capsule strengths. Canadian Pharmacy King is an accredited online pharmacy that offers this medication at a lower cost than the average U.S. retail price. Other medications for the treatment of GERD include:
Prevacid.
The information below lists potential side effects and risks. It is crucial to discuss these with your doctor or pharmacist.
Common Side Effects – The following are common side effects of Dexilant. Contact your doctor if you experience these side effects and they are severe or bothersome.
• Abdominal pain
• Diarrhea
• Flatulence (gas)
• Nausea
• Upper respiratory tract infection
• Vomiting
Other Potential Side Effects (less common) – These effects are reported less frequently but can still occur:
• Anxiety
• Dizziness
• Dry mouth
• Hypertension (high blood pressure)
• Insomnia
• Weight gain
Serious Side Effects - These are rare but potentially severe. Seek your doctor or call medical emergency services immediately if any of the following occur:
• Acute Tubulointerstitial Nephritis: A sudden form of kidney inflammation that can occur at any point during treatment and may lead to kidney failure.
• Bone Fractures: An increased risk of hip, wrist, or spine fractures, especially in patients who take high doses or use the medication for a year or longer.
• Clostridioides difficile-Associated Diarrhea: A severe bacterial infection in the colon that causes persistent watery stools, stomach pain, and fever.
• Hypomagnesemia: Pathologically low magnesium levels (usually after a year of use), which can cause tremors, seizures, or heart arrhythmias.
• Severe Cutaneous Adverse Reactions: Including Stevens-Johnson Syndrome and toxic epidermal necrolysis, which are life-threatening skin reactions.
• Systemic Lupus Erythematosus: The development of new or worsening autoimmune symptoms, such as joint pain or a skin rash on the cheeks that worsens in sunlight.
• Vitamin B12 Deficiency: Long-term use (longer than 3 years) can interfere with the absorption of Vitamin B12, leading to anemia or nerve damage.
While Dexilant is highly effective for managing acid reflux, there are absolute contraindications to its use. Dexilant is not known to be contraindicated in patients with iron overload disorders or hypervitaminosis. However, because Dexilant reduces stomach acid, it may interfere with iron supplement absorption. Patients with iron-deficiency anemia should have their iron levels monitored, but those with hemochromatosis do not need to avoid this medication for safety reasons.
Beyond these contraindications, a medical consultation is required before starting Dexilant to ensure it is safe given your health history. You should discuss this medication with a healthcare provider if you have a history of alcohol use or abuse, kidney disease (mineral levels may need adjustment due to reduced function), liver problems, or stomach or intestinal issues such as ulcers or colitis Longterm use of Dexilant (typically longer than three years) may lead to a Vitamin B12 deficiency because stomach acid is required for the body to absorb B12 from food. Patients should be monitored for signs of deficiency, such as fatigue or tingling in the extremities, rather than concerns that the medication is masking these symptoms. Additionally, patients taking warfarin or methotrexate require close monitoring due to the risk of increased drug levels and potential toxicity.
Dietary and Lifestyle Factors
While Dexilant provides relief through its DDR technology, its effectiveness is enhanced when paired with lifestyle adjustments that reduce physical pressure on the lower esophageal sphincter. Patients are encouraged to identify personal "trigger foods"—commonly acidic citrus, spicy dishes, high-fat meals, caffeine, and alcohol—that can aggravate the esophageal lining despite medication. Beyond diet, lifestyle modifications such as maintaining a healthy weight, quitting smoking, and eating smaller portions are vital. To prevent nighttime reflux, it is clinically recommended to wait at least 3 hours after eating before lying down and to use a wedge pillow to keep the head elevated, allowing gravity to keep gastric contents in the stomach.
Where can I buy Dexilant online?
You can buy Dexilant online from our certified Canadian Pharmacy, or by email (CustomerService@canadianpharmacyking.com), by phone (1-877-745-9217), or by fax or mail.
Do I need a prescription to buy Dexilant?
A prescription is required to purchase Dexilant from a CIPA-verified Canadian pharmacy.
How much does Dexilant cost?
Dexilant costs can vary depending on the brand, dosage, quality, and supplier country. At Canadian Pharmacy King, we are proud to offer highly competitive prices on Dexilant.
Can I use a prescription discount card or coupon to save on Dexilant?
Unfortunately, there is no discount card or coupons for Dexilant. Choosing a generic version or a three-month supply can help you lower the cost of Dexilant.
Can I buy Dexilant over-the-counter?
No, you cannot buy Dexilant over the counter. A prescription is required to order Dexilant.
What is the shipping time for Dexilant orders from Canada to the USA?
It may take 4-8 business days for a Dexilant order shipped from Canada. If you have any questions about the shipping timeframe, please contact our customer support team at 1-877-745-9217 for details.