Desyrel (Trazodone) is a prescription medication that is used to treat depression. This medication will help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related to depression. Trazodone is an antidepressant that belongs to a group of drugs called serotonin receptor antagonists and reuptake inhibitors (SARIs). It works by increasing the amount of serotonin, a natural substance in the brain that helps maintain mental balance.

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Seek emergency medical help if you have any signs of an allergic reaction to this medication.

The common side effects of Desyrel may include blurred vision, constipation, diarrhea, dizziness, drowsiness, fatigue, stuffy nose, swelling, and weight loss.

Contact your doctor immediately if any of these serious side effects occur:
• Easy bruising or unusual bleeding;
• Fast or pounding heartbeats, fluttering in your chest;
• Symptoms of low levels of sodium in the body;
• Slow heartbeats;
• Sudden dizziness, shortness of breath;
• Unusual thoughts or behavior

This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.

Do not use Desyrel if you are allergic to Trazodone or if you have used an MAO inhbitor in the past 14 days.

Prior to taking this medication, tell your doctors about your medical history and if you have ever had:
• A bleeding or blood clotting disorder;
• A recent heart attack or have heart disease;
• Bipolar disorder;
• Drug addiction or suicidal thoughts;
• Liver or kidney disease;
• Long QT syndrome;
• Narrow-angle glaucoma;
• Seizures or epilepsy

Some young people have thoughts about suicide when first taking an antidepressant; get your progress checked by your doctor regularly. Do not drink alcohol; it can cause dangerous side effects including death. Your reactions could be impaired; avoid driving or any hazardous activity until you know how this medication affects you. Do not get up too fast from sitting or lying position or you may feel dizzy. Do not start or stop taking Desyrel without your doctor's advice. Tell your doctor about all the medications you take including prescription, nonprescription, herbal products, and vitamins. There may be a drug interaction between Desyrel and other medications such as other antidepressants, diuretics, blood thinners, migraine medications, etc. Pregnant women may have to get their name listed on a pregnancy registry to track the effects of Trazodone on the baby. Consult your doctor before breast-feeding. Desyrel is not approved for use by anyone younger than 18 years of age.

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