Coversyl Plus (Perindopril/Indapamide) is a prescription medication used to treat high blood pressure. Left untreated, high blood pressure can damage vital organs, leading to conditions like heart failure, stroke, heart attack, vision loss, and kidney problems. Coversyl Plus is a combination medicine. The active ingredients in Coversyl Plus are Perindopril and Indapamide. Perindopril belongs to a class of drugs called angiotensin-converting enzyme (ACE) inhibitors. It works by relaxing the blood vessels and helping the heart to pump oxygen-rich blood more efficiently to different parts of the body. Indapamide belongs to a class of drugs called diuretics. It works by removing excess salt and water, thereby helping the body regulate blood pressure.
Manufacturer Information
We currently offer the brand Coversyl Plus from Canada, manufactured by Servier, in strengths of 2 mg/0.625 mg, 4 mg/1.25 mg, and 8 mg/2.5 mg tablets. The generic Perindopril/Indapamide is currently unavailable (at this pharmacy).
Get medical help immediately if you have any of these signs or an allergic reaction while using Coversyl Plus. The most common side effects of Coversyl Plus may include the following:
• Abdominal pain;
• Appetite loss;
• Diarrhea;
• Drowsiness;
• Dry and persistent cough;
• Dry mouth
Contact your doctor right away if you have any of the severe side effects, including:
• Chest pain;
• Mood swings;
• Muscle cramps;
• Signs of an allergic reaction, such as trouble breathing, hives, swelling of the face, lips, or throat;
• Signs of anemia, such as dizziness, pale skin, unusual tiredness or weakness, shortness of breath;
• Signs of dehydration, such as significantly decreased urine output, dry skin, headache, extreme thirst, dizziness, and confusion
These are not all of the side effects of Coversyl Plus. Always contact your doctor if you notice any unusual symptoms.
You should not use Coversyl Plus if you are allergic to Perindopril, Indapamide, or any ingredient in Coversyl Plus. Before you start using this medication, tell your doctor about your medical history, especially if you:
• Are allergic to sulfa medicines;
• Are breastfeeding or planning to breastfeed;
• Are pregnant or planning to become pregnant;
• Have a history of angioedema after taking ACE inhibitors;
• Have bilateral renal artery stenosis;
• Have decreased liver function;
• Have diabetes;
• Have electrolyte imbalance;
• Have kidney problems;
• Have lactose or galactose intolerance
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Coversyl Plus and other medications, such as aliskiren, allopurinol, amiodarone, losartan, captopril, cetirizine, atropine, digoxin, drospirenone, levodopa, lithium, and tacrolimus. Tell your doctor if you are pregnant or planning to become pregnant. Perindopril can harm an unborn baby if taken during pregnancy. Use effective birth control to prevent pregnancy when taking this drug. Inform your doctor if you are breastfeeding or planning to breastfeed. Perindopril passes into breast milk and may harm a nursing infant. It is unknown if Indapamide passes into breast milk. Do not breastfeed while taking this medication.
Use this medicine exactly as prescribed by your doctor. Coversyl Plus comes as tablets. Swallow the tablets whole with a glass of water. Do not crush, chew, or break them. Your doctor will conduct regular blood tests to monitor your blood count. You may develop a persistent, dry cough when using this medicine. This usually disappears after stopping the medication. Coversyl Plus can cause dizziness. Do not stand up too fast from a sitting or lying position to reduce your risk of falls. Be cautious if you drive or engage in any activity that requires you to be alert. Indapamide may increase your sensitivity to the sun (photosensitivity). Avoid exposure to excessive sunlight. Use sunscreen with an SPF of at least 30 and wear protective clothing when outdoors. Store this drug at room temperature, away from light and moisture. Keep out of the reach of children.