Combigan (Brimonidine/Timolol) is an ophthalmic solution (eye drops). Brimonidine reduces the amount of fluid in the eye, which decreases pressure inside the eye and Timolol is a beta-blocker that also reduces pressure inside the eye. Combigan eye drops are used for the treatment of open-angle glaucoma or ocular hypertension (high pressure inside the eye).
We currently have the brand Combigan from Canada and India manufactured by Allergan. Combigan is available in two strengths: 0.2 %/0.5 %/5 ml and 0.2 %/0.5 %/10 ml.
Call you doctor immediately if you have:
• Difficulty breathing;
• Swelling of the face or throat;
• Symptoms of a severe allergic reaction
Less serious side effects include:
• Drowsiness, tired feeling;
• Mild itching, redness, or irritation of your eyes;
• Mild stinging or burning when using the eye drops
You should not use Combigan eye drops if you are allergic to Brimonidine or Timolol. Combigan should not be given to a child younger than 2 years old. It is unknown whether Combigan will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Timolol and Brimonidine can pass into breast milk and may harm a nursing baby. You should not breast-feed while using this medicine. There may be an interaction between Brimonidine–Timolol eye drops and other medications such as alcohol, clonidine, dronedarone, epinephrine, high blood pressure medications, tricyclic antidepressants, etc.