COLAZAL (balsalazide disodium) Capsules 750 mg delivers 5-aminosalicyclic acid (5-ASA), an anti-inflammatory drug, to the site of inflammation in the colon. Approximately 99% of an administered dose reaches the colon intact, where the 5-ASA works topically. 5-ASA appears to have multiple sites of impact on the immune system and the inflammatory process that characterizes ulcerative colitis. Patients are advised to swallow COLAZAL capsules whole.
The recommended adult prescription dose for the treatment of active ulcerative colitis is three 750 mg COLAZAL capsules, taken 3 times a day for a total daily dose of 6.75 g for a duration of 8 weeks. Some patients in clinical trials required treatment for up to 12 weeks.
SIDE EFFECTS, that may go away during treatment include, abdominal pain, diarrhea, joint or muscle pain, runny or stuffy nose, loss of appetite, heartburn, or coughing. If they continue or are bothersome, check with your doctor. CHECK WITH YOUR DOCTOR IMMEDIATELY if you experience nausea, yellowing skin or eyes, dark urine, fever, or fatigue. If you notice other effects not listed above, contact your doctor, nurse, or pharmacist.