This is a prescription medication used to treat hypertension (high blood pressure). It is a cardioselective beta-1 (ß1) adrenergic receptor blocker with endothelium-dependent vasodilating properties. Beta-blockers affect the heart and circulation (blood flow through arteries and veins). It works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels. By lowering blood pressure, it reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and heart attacks.
The study by Fongemie and Felix-Getzik (2015) provides a detailed overview of nebivolol, a distinctive third-generation B1-selective blocker. Unlike traditional agents, it promotes nitric oxide-mediated vasodilation, effectively lowering peripheral and central blood pressure while preserving cardiac output. The review emphasizes that this mechanism results in a significantly lower side-effect profile than that of older blockers such as atenolol or metoprolol. Clinical evidence supports its use for hypertension and heart failure, particularly in patients concerned with metabolic issues or erectile dysfunction. In summary, it offers a unique pharmacological profile that improves both tolerability and therapeutic options in cardiovascular treatment.
Manufacturer Information
We currently have the brand-name product (also known as Vasoxen), manufactured by AbbVie, available in Canada and Turkey.
Generic Bystolic is currently available from a Canadian manufacturer and may also be sourced from international suppliers. Please check our website for the latest updates.
Both the brand-name and generic versions come in oral tablets with strengths of 2.5 mg, 5 mg, and 10 mg. The brand version also offers a 20 mg tablet.
The information below lists potential side effects and risks. It is crucial to discuss these with your doctor or pharmacist.
Common Side Effects – The following are common side effects. Contact your doctor if you experience these side effects and they are severe or bothersome.
• Dizziness
• Fatigue
• Headache
• Nausea
• Paresthesia (numbness or tingling sensation)
• Peripheral edema (swelling of the legs or hands)
Other Potential Side Effects: (less common) – These effects are reported less frequently but can still occur:
• Abdominal pain
• Bradycardia (slow heart rate)
• Diarrhea
• Dyspnea (shortness of breath)
• Erectile dysfunction
• Insomnia
• Rash
Serious Side Effects - These are rare but potentially severe. Seek your doctor or call medical emergency services immediately if any of the following occur:
• Bronchospasm (Sudden constriction of the airways, particularly in those with asthma or COPD)
• Congestive heart failure exacerbation
• Hypersensitivity reactions (Angioedema or anaphylaxis)
• Severe bradycardia or heart block (Interruption of electrical signals in the heart)
• Significant elevations in liver enzymes (seek medical attention if you notice yellowing of the eyes/skin or dark urine)
You should not use this medication if you have severe bradycardia, heart block greater than first degree, or decompensated heart failure. Before starting treatment, discuss your medical history and all current medications with your healthcare provider, especially: CYP2D6 inhibitors, heart rate modulators, and specialized inducers.
Beta-blockers can hide symptoms of low blood sugar in diabetics and may worsen breathing issues in those with asthma or COPD. If you have a history of severe allergies, be aware that these medications can increase your sensitivity to allergens. Talk to your doctor if you are pregnant or breastfeeding, as the drug may impact placental blood flow or the newborn.
Dietary and Lifestyle Factors
To achieve optimal results and ensure safety while undergoing this blood pressure treatment, exercise caution and monitor your blood pressure.
While nebivolol is more metabolically friendly than older blockers, a heart-healthy diet low in sodium and saturated fats can help support its effectiveness. If you notice unusual coldness in your extremities, inform your doctor, as beta-blockers can sometimes affect peripheral circulation.
How do I order?
You can order this medication from our website, or by email (CustomerService@canadianpharmacyking.com), by phone (1-877-745-9217), or by fax or mail.
Is a prescription required?
Yes, a prescription is required when purchasing this medication.
Can I get a prescription in the USA and use it to buy medication from Canada?
Yes, you can get a prescription from your physician in the USA and use it to buy from a Canadian pharmacy.
Are there any discounts or coupons available?
Unfortunately, no discounts or coupons are available. However, we are proud to offer high-quality prescription medications at affordable prices.
Can I have this medication shipped from Canada to my address in the USA?
Yes, you can get it shipped to your address (or home) in the USA from Canada.
What are the shipping costs and delivery times from Canada to the USA?
It may take 4-8 business days for your order to ship from Canada, and our shipping cost to the area is $10.00. If you have any questions about the shipping frame, please get in touch with our customer support at 1-877-745-9217 for details.
How can I tell if an online pharmacy is legitimate?
Any CIPA-certified pharmacy is licensed, reputable, and must follow strict safety protocols. CanadianPharmacyKing.com is verified by the Canadian International Pharmacy Association (CIPA).