You should not use Buscopan if you are allergic to hyoscine butylbromide, or if you are allergic to atropinic medications such as atropine and scopolamine. As well, you should not use this medication if you have myasthenia gravis, megacolon (enlarged colon), glaucoma, or if you have obstructive prostatic hypertrophy (enlarged or blocked prostate). You should not use the injection form of this medication if you are taking a blood thinner medication (i.e. warfarin, heparin), if you have a narrowing of the gastrointestinal tract, if you have a fast heartbeat, or if you have heart failure. To make sure this medication is safe for you, tell your doctor if you have ever had prostate problems, high blood pressure, digestive problems, or autonomic neuropathy. Tell your doctor if you are pregnant or breastfeeding in order to discuss any possible risks. Buscopan is not approved for use in children under 12 years old.
Buscopan may interact with several medications, especially antihistamines (i.e. cetirizine, doxylamine, diphenhydramine), antipsychotics (i.e. chlorpromazine, clozapine, haloperidol), barbiturates (i.e. butalbital, pentobarbital, phenobarbital), benzodiazepines (i.e. alprazolam, diazepam, lorazepam), general anesthetics, MAO inhibitors (i.e. moclobemide, phenelzine, rasagiline), muscle relaxants (i.e. cyclobenzaprine, methocarbamol, orphenadrine), narcotic pain relievers (i.e. codeine, fentanyl, morphine), seizure medications (i.e. clobazam, levetiracetam, phenytoin), selective serotonin reuptake inhibitors (SSRIs; i.e. citalopram, fluoxetine, sertraline), thiazide diuretics (water pills; i.e. hydrochlorothiazide, metolazone), or tricyclic antidepressants (i.e. amitriptyline, desipramine, nortriptyline). This is not a complete list of interactions, and others may occur. Tell your doctor about any medications, vitamins, or herbal supplements you are currently taking or have recently taken in order to reduce the risk of interactions.
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