Breztri Aerosphere (Budesonide/Glycopyrrolate/Formoterol Fumarate) is an inhaler that contains 3 medications and is used to control and prevent symptoms such as wheezing, shortness of breath caused by ongoing lung disease such as COPD, including chronic bronchitis and emphysema. Breztri Aerosphere has proven to reduce COPD flare-ups. Using this medication will help you maintain your normal activities and decrease time lost from work or school. Budesonide belongs to a class of drugs known as corticosteroids. It works by reducing the swelling and irritation of the airways. Glycopyrrolate is an anticholinergic and formoterol fumarate is a long-acting beta agonist. They work by relaxing muscles around the airways so that they can open up.
We currently offer the brand Breztri Aerosphere from Australia and the United Kingdom (Trixeo Aerosphere) by AstraZeneca. The generic version is not available.
Seek emergency medical help if you have any signs of an allergic reaction to this medication. The common side effects of Breztri Aerosphere may include back pain, cough, diarrhea, difficulty sleeping, feeling anxious, flu, headache, high blood sugar levels, hoarseness, inflammation of the sinuses, joint pain, muscle spasms, nausea, painful or frequent urination, pneumonia, upper respiratory tract infection, and thrush in your mouth and throat.
Contact your doctor immediately if any of these serious side effects occur:
• Adrenal insufficiency;
• Bone thinning or weakness;
• Changes in laboratory blood values;
• Effects on your heart;
• Effects on your nervous system;
• Fungal infection in your mouth or throat;
• New or worsening eye problems such as narrow-angle glaucoma and cataracts;
• Sudden breathing problems after inhaling the medication;
• Urinary retention
This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.
You should not use Breztri Aerosphere if you are allergic to Budesonide, Glycopyrrolate, Formoterol, or any of the ingredients in this medication. Prior to taking this medication, tell your doctors about your medical history and if you are exposed to chickenpox or measles, pregnant or plan to become pregnant, or are breastfeeding or if you have:
• An immune system problem;
• Any type of viral, bacterial, parasitic, or fungal infection;
• Eye problems;
• Heart problems;
• High blood pressure;
• Liver or kidney problems;
• Prostate or bladder problems, or problems with urinating;
• Thyroid problems;
• Weak bones
This medication may mask signs of infection. It can make you more likely to get infections or may worsen any current infections. Avoid contact with people who have infections that may spread to others. Tell your doctor about all the medications you take including prescription, nonprescription, herbal products, and vitamins. There may be a drug interaction between Breztri Aerosphere and other medications such anticholinergics, other LABAs, atropine, antifungal or anti-HIV medications.
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