Bijuva (Estradiol Hemihydrate/Progesterone) is a prescription medicine that contains two kinds of hormones, an estrogen and a progestogen. Bijuva is used after menopause to reduce moderate to severe hot flashes in women who has not had her uterus removed. Estrogens are hormones made by a woman’s ovaries. The ovaries normally stop making estrogens when a woman is between 45 and 55 years old. This drop in body estrogen levels causes the “change of life” or menopause (the end of monthly menstrual periods). When estrogen levels begin dropping, some women get very uncomfortable symptoms, such as feelings of warmth in the face, neck, and chest, or sudden intense feelings of heat and sweating (“hot flashes” or “hot flushes”). In some women the symptoms are mild, and they will not need to take estrogens. In other women, symptoms can be more severe. Take Bijuva exactly as your healthcare provider tells you to take it. Take Bijuva by mouth each evening with food. Estrogens should be used at the lowest dose possible for your treatment and only as long as needed. You and your healthcare provider should talk regularly (for example, every 3 to 6 months) about whether you still need treatment with Bijuva.
Canadian Pharmacy King currently offers the brand Bijuva from Canada by Knight Therapeutics Inc. in the strength of 0.5 mg/100mg and 1 mg/100 mg capsules. The generic alternative is currently unavailable.
Common side effects of Bijuva may include breast tenderness vaginal bleeding; pelvic pain; headache; vaginal discharge. Call your doctor immediately if you notice more serious side effects such as:
• A breast lump;
• High levels of calcium in your blood;
• Signs of a stroke;
• Signs of a blood clot;
• Swelling or rapid weight gain;
• Symptoms of a heart attack;
• Unusual vaginal bleeding
This is not a complete list of side effects, and others may occur. Contact your doctor if any of these side effects worsen or persist.
Do not start using Bijuva if you have any unusual vaginal bleeding; have been diagnosed with a bleeding disorder; currently have or have had certain cancers; currently have or have had blood clots; had a stroke or heart attack; currently have or have had liver problems; are allergic to Bijuva or any of its ingredients. Before you use Bijuva, tell your healthcare provider about all of your medical conditions, including if you have high levels of fat in your blood (triglycerides); have any unusual vaginal bleeding; have any other medical conditions; asthma (wheezing); epilepsy (seizures); diabetes; problems with your heart, liver, thyroid or kidneys or have high calcium in your blood; are going to have surgery; are pregnant or think you may be pregnant; are breastfeeding. The hormones in Bijuva can pass into your breast milk. Smoking while taking this medication can increase your risk of blood clots, stroke, or heart attack, do not smoke. Avoid the use of grapefruit products; it may interact with this medication and lead to unwanted side effects. Tell your healthcare provider about all the medicines you take, including prescription and over-the-counter medicines, vitamins, and herbal supplements. Some medicines may affect how Bijuva works.
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