Antizol (Fomepizole) is a prescription medication used to treat poisoning with ethylene glycol (antifreeze) or methanol (in fuels, solvents, and other household automotive chemicals). This drug is sometimes used with hemodialysis to rid the body of a poison. Poison deprive the body’s cells of oxygen or activates or block enzymes and receptors, causing bodywise symptoms. Changes in body temperature, consciousness, heart rate, and breathing, depending on the organs affected, are symptoms of poisoning. Antizol is an injection administered into a vein. The active ingredient in Antizol is Fomepizole. Fomepizole belongs to a class of drugs called antidotes. It works by blocking the enzyme that breaks down methanol and ethylene glycol to their toxic products.
We currently offer the brand Antizol from Canada manufactured by Paladin in the strength of 1gm/ml vials. The generic Fomepizole is not available.
Get medical help immediately if you have any of these signs or an allergic reaction while receiving Antizol. The most common side effects of Antizol may include the following:
• Metallic taste in your mouth
Contact your doctor right away if you have any of the severe side effects, including:
• A light-headed feeling, like you might pass out;
• Muscle weakness;
• Severe allergic reaction including breathing difficulties, itching, skin rash, swelling of the face, tongue, or throat;
• Severe nausea;
• Severe tingling
These are not all of the side effects of Antizol. Always contact your doctor if you notice any unusual symptoms.
You should not receive Antizol if you are allergic to Fomepizole or any ingredient in Antizol. Before you start using this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or planning to breastfeed;
• Are pregnant or planning to be pregnant;
• Have difficulty urinating;
• Have kidney disease;
• Recently drank alcohol
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Antizol and cimetidine, ketoconazole, carbamazepine, phenytoin, etc. Tell your doctor if you are pregnant or planning to become pregnant. It is not known whether Antizol will harm an unborn baby. Inform your doctor if you are breastfeeding or planning to breastfeed. It is not known if Fomepizole passes into breast milk or if it may affect a nursing infant. Use Antizol precisely as prescribed by your doctor. This drug is infused directly into your vein over 30 minutes. Your doctor may use Antizol alone or in combination with kidney dialysis. Antizol vials are for single use only. Discard unused portions. Store at 200 to 250C.