You should not use Angeliq if you are allergic to drospirenone or estradiol, or if you have vaginal bleeding, a bleeding disorder, coronary artery disease, a history of heart attack, stroke, or blood clot, kidney disease, liver disease, an adrenal gland disorder, a history of hormone-related cancer, or if you have had your uterus removed (hysterectomy). Tell your doctor if you have ever had heart disease, high blood pressure, a thyroid disorder, gallbladder disease, jaundice caused by pregnancy or taking hormones, high triglycerides, asthma, epilepsy, migraine headaches, lupus, endometriosis, high levels of calcium or potassium in your blood, low sodium levels, hereditary angioedema, or porphyria. Do not use this medication if you are pregnant. Tell your doctor right away if you become pregnant during treatment. You should not breast feed while using this medication. Avoid smoking while using this medication, as it can greatly increase your risk of blood clots, stroke, or heart attack while using this medication. Angeliq has not been approved for use in children.
Angeliq may interact with some medications, including aromatase inhibitors (i.e. anastrozole, exemestane), atazanavir/cobicistat, corticosteroids (i.e. prednisone), ospemifene, raloxifene, tamoxifen, tizanidine, tranexamic acid, and warfarin. This is not a complete list of medications, and others may interact. Tell your doctor about any medications, herbal supplements, or vitamins you are currently taking or have recently taken in order to reduce the risk of possible interactions.
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