This is a combination medication that includes a steroid and a bronchodilator. It is used for the long-term maintenance treatment of asthma and COPD. It should not be used to treat sudden, acute symptoms or an active asthma attack. Additionally, it helps prevent flare-ups or worsening of chronic obstructive pulmonary disease (COPD) related to chronic bronchitis or emphysema. Managing these symptoms may reduce time lost from work or school. Fluticasone is a corticosteroid that reduces airway irritation and swelling. Salmeterol is a long-acting beta agonist that helps open the airways in the lungs, making breathing easier.
The New England Journal of Medicine published a study showing that combining fluticasone and salmeterol in children with persistent asthma does not increase the risk of serious asthma-related events compared to using fluticasone alone. The combination therapy significantly lowered the rate of asthma exacerbations. These findings offer strong clinical evidence for the safety and greater effectiveness of this "step-up" approach in pediatric patients.
Manufacturer Information
We currently have the brand-name product from GSK in Turkey and New Zealand. It comes in strengths of 50 mcg/25 mcg/120 doses, 125 mcg/25 mcg/120 doses, and 250 mcg/25 mcg/120 doses.
The generic Fluticasone/Salmeterol inhaler, also known as the Seroflo Inhaler, is manufactured by Cipla in India. It is available in strengths of 50 mcg/25 mcg/120 doses and 125 mcg/25 mcg/120 doses.
The information below lists potential side effects and risks. It is crucial to discuss these with your doctor or pharmacist.
Common Side Effects – The following are common side effects. Contact your doctor if you experience these side effects and they are severe or bothersome.
• Bronchitis
• Cough
• Dizziness
• Headaches
• Hoarseness and voice changes (dysphonia)
• Nausea and vomiting
• Sore throat and throat irritation
• Upper respiratory tract infection
Other Potential Side Effects: (less common) – These effects are reported less frequently but can still occur:
• Diarrhea
• Insomnia
• Musculoskeletal pain
• Palpitations
• Stomach pain
• Tremor (shaking)
• Viral respiratory infections
Serious Side Effects - These are rare but potentially severe. Seek your doctor or call medical emergency services immediately if any of the following occur:
• Adrenal Suppression:
• Hypokalemia
• Immediate Hypersensitivity
• Paradoxical Bronchospasm
• Pneumonia
• Thrush (Oropharyngeal Candidiasis)
You should not use the Advair Inhaler if you are allergic to fluticasone, salmeterol, or any other ingredients. Before starting treatment, discuss your complete medical history and all medications you are taking with your healthcare provider, especially focusing on:
• Antifungals and Antivirals: Ketoconazole, boceprevir, and cobicistat.
• Antibiotics and Antidepressants: Macrolide antibiotics, telithromycin, and nefazodone.
• HIV Protease Inhibitors: Lopinavir and ritonavir.
Long-term use may slow a child’s growth, but uncontrolled asthma also affects development; therefore, growth should be monitored by a pediatrician. This medication may raise your blood pressure so that you may need regular blood pressure checks. It should not be used during pregnancy unless necessary, and since it is unknown if the medication passes into breast milk, you should consult your doctor before breastfeeding.
Dietary and Lifestyle Factors
Achieving therapeutic stability with this medication requires specific routine adjustments to manage potential side effects and environmental triggers. To lower the risk of localized immunosuppression and subsequent oral thrush, you must:
•
Rinse your mouth with water and spit it out after every dose.
•
Maintain a diet high in Calcium and Vitamin D to support long-term bone health during corticosteroid therapy.
Since it is a maintenance-only medication, it is important to always keep a separate, fast-acting rescue inhaler nearby for sudden, severe bronchospasms. Proactively managing the environment—including avoiding tobacco smoke, known allergens, and extreme cold—is vital for controlling underlying airway inflammation. Additionally, because some patients might experience temporary tremors or dizziness, you should avoid driving or operating heavy machinery until you're certain the medication does not impair your coordination or alertness.
How do I order?
You can order this medication from our website, or by email (CustomerService@canadianpharmacyking.com), by phone (1-877-745-9217), or by fax or mail.
Is a prescription required?
Yes, a prescription is required when purchasing this medication.
Can I get a prescription in the USA and use it to buy medication from Canada?
Yes, you can get a prescription from your physician in the USA and use it to buy from a Canadian pharmacy.
Are there any discounts or coupons available?
Unfortunately, no discounts or coupons are available. However, we are proud to offer high-quality prescription medications at affordable prices.
Can I have this medication shipped from Canada to my address in the USA?
Yes, you can have this medication shipped to your address (home) in the USA from Canada.
What are the shipping costs and delivery times from Canada to the USA?
It may take 4-8 business days for your order to ship from Canada, and our shipping cost to the area is $10.00. If you have any questions about the shipping frame, please get in touch with our customer support at 1-877-745-9217 for details.
How can I tell if an online pharmacy is legitimate?
Any CIPA-certified pharmacy is licensed, reputable, and must follow strict safety protocols. CanadianPharmacyKing.com is verified by the Canadian International Pharmacy Association (CIPA).