Orforglipron (Orforglipron) is a prescription experimental medication indicated for the treatment of Type 2 diabetes and weight loss in people with obesity. Type 2 diabetes is a chronic condition that presents with persistently high blood sugar levels. This condition occurs when the body does not use insulin properly or produce enough of it, consequently affecting how the body uses sugar (glucose) for energy. The active ingredient in Orforglipron is Orforglipron. Orforglipron belongs to a class of drugs called non-peptide glucagon-like peptide-1 (GLP-1) receptor agonists. It works by binding to GLP-1 receptors and stimulating insulin release from the pancreas when it is needed. It also slows down gastric emptying, which is how fast-food travels from the stomach to the small intestine. This can help you feel fuller for longer, reduce how much you eat, and lead to weight loss.
Manufacturer Information
We currently offer the brand Orforglipron from Canada manufactured by Eli Lilly (unavailable). The generic Orforglipron is not available.
Get medical help immediately if you have any of these signs or an allergic reaction while using Orforglipron. The most common side effects of Orforglipron may include the following:
• Constipation;
• Diarrhea;
• Indigestion;
• Nausea;
• Vomiting
Contact your doctor right away if you have any of the severe side effects, including:
• Gallbladder problems, such as gallstones or inflammation;
• Pancreatitis;
• Signs of an allergic reaction, such as trouble breathing, hives, swelling of the face, lips, or throat
These are not all of Orforglipron's side effects. Always contact your doctor if you notice any unusual symptoms.
You should not use Orforglipron if you are allergic to Orforglipron or any ingredient in Orforglipron. Before you start using this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or planning to breastfeed;
• Are pregnant or planning to become pregnant;
• Have a family or personal history of medullary thyroid carcinoma (MTC) or multiple endocrine neoplasia syndrome type 2 (MEN 2);
• Have a history of gastroparesis;
• Have a history of pancreatitis;
• Have severe gastrointestinal disorders
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between the Orforglipron and other medicines, such as insulin, sulfonylureas, oral contraceptives, etc. Tell your doctor if you are pregnant or planning to become pregnant. Orforglipron is not recommended for use in pregnancy. Discuss alternative options with your doctor. Inform your doctor if you are breastfeeding or planning to breastfeed. Orforglipron is not recommended for use when breastfeeding. Discuss alternative treatments with your doctor when breastfeeding.
Use this medicine exactly as your doctor prescribes. Orforglipron comes as a tablet. Swallow this medicine whole. Do not crush, chew, or break it. This medicine is a once-daily oral pill. You can take Orforglipron at any time of the day without restrictions on food and water intake. Store this drug at room temperature, away from light and moisture. Keep out of the reach of children.