Clindoxyl Gel (Clindamycin/Benzoyl Peroxide) is a prescription medication used to moderate acne vulgaris. Acne vulgaris is a common skin condition characterized by the presence of comedones (blackheads and whiteheads), papules, and pustules (also known as pimples). The active ingredients in Clindoxyl Gel are Clindamycin and Benzoyl Peroxide. Clindamycin belongs to a class of drugs called antibiotics. It works by inhibiting the growth of the bacteria responsible for acne. Benzoyl Peroxide belongs to a class of medications known as antibacterials and keratolytic agents. As an antibacterial, it works by penetrating the skin and killing the bacteria that cause acne. As a keratolytic, it helps to soften and peel the outer layer of the skin, which helps to remove excess dead skin cells and prevent pores from becoming clogged.
Manufacturer Information
We currently offer the brand Clindoxyl Gel from Canada, manufactured by GSK, in strengths of 1 %/3 %/45 gm and 1 %/5 %/45 gm gel. The generic Clindamycin/Benzoyl Peroxide is currently unavailable (at this pharmacy).
Get medical help immediately if you have any of these signs or an allergic reaction while using Clindoxyl Gel. The most common side effects of Clindoxyl Gel may include the following:
• Itching or burning at the application site;
• Mild stinging;
• Redness;
• Skin dryness;
• Skin peeling
Contact your doctor right away if you have any of the severe side effects, including:
• Signs of an allergic reaction, such as trouble breathing, hives, swelling of the face, lips, or throat;
• Signs of gastrointestinal symptoms, such as severe, watery, or bloody diarrhea, stomach cramps, and bloating
These are not all of the side effects of Clindoxyl Gel. Always contact your doctor if you notice any unusual symptoms.
You should not use Clindoxyl Gel if you are allergic to Clindamycin, Benzoyl Peroxide, or any of the ingredients in Clindoxyl Gel. Before you start using this medication, tell your doctor about your medical history, especially if you:
• Are breastfeeding or planning to breastfeed;
• Are pregnant or planning to become pregnant;
• Have a history of inflammatory bowel disease, such as Crohn’s disease or ulcerative colitis;
• Have a history of severe or bloody diarrhea after using antibiotics
Tell your doctor about all your medications, including prescription, OTC, herbal supplements, and vitamins. There may be drug interactions between Clindoxyl Gel and other medications, such as tretinoin, tazarotene, erythromycin, sulfonamides, and pancuronium. Tell your doctor if you are pregnant or planning to become pregnant. Clindoxyl Gel is generally not recommended during pregnancy unless the potential benefits outweigh the risks. Animal studies have shown potential harmful effects on the fetus. Consult your doctor if you are pregnant or planning to become pregnant. Inform your doctor if you are breastfeeding or planning to breastfeed. It is not known if Clindamycin passes into breast milk when applied topically. If you are using this medication when breastfeeding, do not apply it to the chest or breast area to prevent the infant from ingesting it.
Use this medicine exactly as your doctor prescribes it. Clindoxyl Gel is a gel. Apply this medication once daily, in the evening. Please do not take it by mouth. Clean the affected area of your skin with a mild cleanser and pat dry. Apply a thin layer of the gel to the entire affected area, not just to individual spots. Use your fingertip to apply just enough to cover the area. Do not apply too much, as this may increase skin irritation. Wash your hands thoroughly after application. Avoid contact with your eyes, mouth, nostrils, and other mucous membranes. If accidental contact occurs, rinse the area with plenty of water for at least 5 minutes. Do not apply Clindoxyl Gel on broken, cut, or sunburned skin. This medication can make your skin more sensitive to the sun. Avoid prolonged exposure to sunlight, sunlamps, or tanning beds. Wear protective clothing and use a broad-spectrum sunscreen with an SPF of at least 30 when outdoors. Benzoyl peroxide can bleach hair, clothing, and bed linen. Use caution to avoid contact with these materials. Continue to use the medication for the full duration prescribed by your doctor, even if your acne appears to be improving. It may take 4-6 weeks to see the full effect of the medicine. After dispensing, store this drug below 25 °C and use it within 2 months. Keep the tube tightly closed and out of the reach of children.