Valdoxan (Agomelatine) is a prescription medication that is used for the treatment of depression. Agomelatine belongs to a group of antidepressants called Selective Serotonin Reuptake Inhibitors (SSRIs) and one antidepressant from the serotonin-norepinephrine reuptake inhibitor group called Venlafaxine. This medication works in two ways, by stimulating the MT1 and MT2 receptors and by blocking the 5-HT2C receptors in the brain. You usually see the effects of this medication in about four weeks. If the medication does not start working in about two weeks, then the dose may be increased. The usual dose for Valdoxan is one pill in the evening or at bedtime.
The brand Valdoxan is available from Turkey manufactured by Servier. The generic Agomelatine comes from India also called Agoprex manufactured by Sun Pharmaceuticals. Valdoxan is available in the strength of 25 mg tablets.
The common side effects of Valdoxan may include:
• Abnormail dreams;
• Abdominal pain;
• Back pain;
• Increase in weight;
Stop taking Valdoxan and contact your doctor right away if you have any of the following rare but serious side effects such as:
• Dark urine;
• Itchy skin;
• Light coloured stools;
• Tummy pain;
• Unexpected bruising;
• Unusual tiredness
This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.
You should not take Valdoxan if you are allergic to Agomelatine or if you have any other allergies. Before you start taking this medication, talk to your doctor about you medical history and about all the medications you take including OTC and herbal medications. Take this medication exactly as prescribed by your doctor. When you feel depressed or if you are taking Valdoxan, you may have suicidal thoughts. If this happens, please talk to your doctor right away. You should drink alcohol while you are taking this medication. Smoking can affect the amount of Agomelatine in your body. This medication should only be used during pregnancy if the benefits outweigh the risks to the developing baby.