Buserelin (BYOO-se-rel-in) is used to treat cancer of the prostate gland.
It is similar to a hormone normally released from the hypothalamus gland. When given regularly, buserelin decreases testosterone levels. Reducing the amount of testosterone in the body is one way of treating cancer of the prostate.
Proper Use of This Medicine
Buserelin comes with patient directions. Read these instructions carefully .
For patients using the injection form of this medicine:
Use the syringes provided in the kit. Other syringes may not provide the correct dose. These disposable syringes and needles are already sterilized and designed to be used one time only and then discarded. If you have any questions about the use of disposable syringes, check with your health care professional.
After use, dispose of the syringes and needles in a safe manner. If a special container is not provided, ask your health care professional about the best way to dispose of syringes and needles.
For patients using the nasal solution form of this medicine:
Use the nebulizer (spray pump) provided. Directions about how to use it are included. If you have any questions about the use of the nebulizer, check with your health care professional.
Use this medicine only as directed by your doctor . Do not use more or less of it, and do not use it more often than your doctor ordered. The exact amount of medicine you need has been carefully worked out. Using too much may increase the chance of side effects, while using too little may not improve your condition.
Buserelin sometimes causes unwanted effects such as hot flashes or decreased sexual ability. It may also cause a temporary increase in pain, trouble in urinating, or weakness in your legs when you begin to use it. However, it is very important that you continue to use the medicine, even after you begin to feel better. Do not stop using this medicine without first checking with your doctor .
Dosing- The dose of buserelin will be different for different patients. Follow your doctor's orders or the directions on the label . The following information includes only the average doses of buserelin. If your dose is different, do not change it unless your doctor tells you to do so.
The number of doses you use each day, the time allowed between doses, and the length of time you use the medicine depend on the medical problem for which you are using buserelin .
For prostate cancer:
For nasal dosage forms:
Adults: 200 micrograms (mcg) (2 sprays) into each nostril every eight hours.
For injection dosage forms:
Adults: In the beginning, 500 mcg (0.5 milligrams [mg]) injected under the skin every eight hours. After a time, your doctor may lower your dose to 200 mcg (0.2 mg) once a day.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
The following side effects are symptoms of a flareup of your condition that may occur during the first few days of treatment. After a few days, these symptoms should lessen. However, they may require medical attention. Check with your doctor if any of the following side effects occur or get worse:
Bone pain; numbness or tingling of hands or feet; trouble in urinating; weakness in legs
Other side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. However, check with your doctor if any of the following side effects continue or are bothersome:
Decrease in sexual desire; impotence; sudden sweating and feelings of warmth (``hot flashes'')
Burning, itching, redness, or swelling at place of injection; diarrhea; dry or sore nose (with nasal solution); headache (with nasal solution); increased sweating (with nasal solution); loss of appetite; nausea or vomiting; swelling and increased tenderness of breasts; swelling of feet or lower legs
Other side effects not listed above may also occur in some patients. If you notice any other effects, check with your doctor.