Retrovir (Zidovudine) is an antiretroviral medication. It is used together with other antiviral medicines to delay the progression of HIV infection. Retrovir is also used for the prevention of maternal-fetal HIV transmission. The Human Immunodeficiency Virus (HIV) is a retrovirus. Infection with HIV damages the immune system and can lead to Acquired Immune Deficiency Syndrome (AIDS) and other related illnesses. Retrovir is used together with other antiviral medicines to delay the progression of HIV infection. Retrovir does not cure AIDS or kill the HIV virus, but helps to prevent further damage to the immune system by slowing down the production of new viruses. Take Retrovir exactly as prescribed. Do not alter or share your dose with others without the direct advice of your physician. If a child has difficulty in swallowing a Retrovir capsule, the Retrovir syrup formulation should be prescribed. Retrovir Syrup is available for dosing children who weigh less than 30 kg. Retrovir. Syrup should be used to provide accurate dosage when capsules are not appropriate.
Canadian Pharmacy King currently offers the brand Retrovir from Canada manufactured by GSK. Our Canadian Pharmacy also carries the generic Zidovudine also called Zidovir manufactured by Cipla. Brand Retrovir is available in the strength of 100 mg capsules and the generic Retrovir is available in the strength of 100 mg and 300 mg tablets.
The common side effects of Retrovir may include nausea, vomiting, fever, headache, stomach pain, loss of appetite, muscle pain, low white blood cell count, decrease in the number of cells involved in blood clotting, decreased red blood cells, failure of the bone marrow to produce new blood cells, an increase in lactic acid, feeling depressed, dizziness, not being able to sleep, tingly feelings in the skin, not being able to concentrate, feeling drowsy, seizures, disease of the heart muscle, cough, intestinal gas, changes in the colour of the nails, skin, or the skin inside the mouth, taste disturbance, indigestion, skin rash, sweating, passing urine more often, enlarged breasts in men, general aches and pain, chills, chest pain, flu-like feeling. Contact your doctor right away if you have the following symptoms:
• Lowered red blood cell count resulting in fatigue, breathlessness;
• Low white blood cell count making you more prone to infections
This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.
Retrovir should not be used in patients: who have potentially life-threatening allergic reactions to any component of the formulations, with low blood cell counts or low hemoglobin levels. Before you use Retrovir, talk to your doctor or pharmacist if: you are allergic to any ingredient in this medicine, you have bone marrow problems, you have enlarged liver, hepatitis or other liver diseases, you have kidney disease, you are taking ribavarin as it could cause or worsen anemia. Before you use Retrovir, talk to your doctor or pharmacist if you are pregnant or planning to become pregnant. HIV-infected women should not breastfeed in order to prevent transmission of HIV to a child who may not yet be infected. The ingredients in Retrovir can also pass into your breast-milk.
Tell your doctor before you decide to take any new drugs, even if these are available without a prescription. Drugs that may interact with Retrovir include: atovaquone, bone marrow suppressive agents/cytotoxic agents, clarithromycin, fluconazole, ganciclovir, interferon-alpha, lamivudine, methadone, phenytoin, probenecid, stavudine, valproic acid, and others such as trimethoprimsulfamethoxazole, pyrimethamine, acyclovir and rifampin. For patients receiving combination therapy with Retrovir and zalcitabine, tell your doctor immediately if you have symptoms of peripheral neuropathy (burning, pain, or numbness in the hands or feet) and pancreatitis (abdominal pain, nausea and vomiting).
The generic alternative is not manufactured by the company that makes the brand product.
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