Opsumit (Macitentan) is used to treat pulmonary arterial hypertension (PAH). (PAH) is high blood pressure in the arteries of your lungs. This medication can improve your ability to exercise, improve some of your symptoms, and help slow down the progression of the disease. Macitentan belongs to the class of drugs called endothelin-1 receptor. It works by blocking endothelin that causes the blood vessels to narrow, which increases the pressure required to push the blood through the lungs to get oxygen, decreasing pulmonary blood pressure. Opsumit is taken with or without food usually once daily.
Canadian Pharmacy King currently offers the brand Opsumit tablets from Canada manufactured by Janssen in the strength of 10 mg. There is no generic available for this medication.
The common side effects of Opsumit may include body aches, chills, cough, headache, runny nose and sore throat.
Inform your doctor right away if you have any of the serious side effects such as:
• New or worsening swelling of the hands, ankles or feet;
• Signs of low red blood cell count;
• Unusual weight gain
This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.
You should not take Opsumit if you are allergic to Macitentan or if you have any other allergies. Before you start taking this medication, talk to your doctor about your medical history and about all the medications you take including OTC and herbal medications. This medication should not be used during pregnancy unless it is clearly needed. It may harm an unborn baby. The medication can be absorbed through your skin and lungs and may harm an unborn baby, pregnant women or women who may become pregnant should not handle this medication or breathe the dust from the tablets. It is unknown if this medication passes into breast milk. Talk to your doctor before breast-feeding as it is not recommended while using this medication. There may be a drug interaction between Opsumit and other medications such as ketoconazole, cobicistat, clarithromycin, HIV protease inhibitors, rifamycins, etc.
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