Letairis (Ambrisentan) is a prescription medication used for the treatment of high blood pressure in the lungs (pulmonary arterial hypertension PAH). Ambrisentan belongs to the class of drugs called Endothelin receptor antagonists (ETRAs). This class of drugs prevents the constriction or narrowing of blood vessels thereby enhancing blood flow throughout the body. Ambrisentan works by blocking endothelin, a substance that is made by the body. Endothelin causes the blood vessels to narrow and it also causes abnormal growth of the muscle in the walls of the blood vessels in the lungs, which increases your blood pressure.
Manufacturer Information
Canadian Pharmacy King offers the generic Ambrisentan from Canada. The brand Letairis is not available at this time. This medication is available in the strength of 5 mg and 10 mg tablets.
The common side effects of Letairis may include abdominal or stomach pain, constipation, flushing, headache, runny nose, sinus pain, sore throat, stuffy nose and vomiting.
Inform your doctor right away if you have any of the serious side effects such as:
• Extreme fatigue;
• Fast heartbeat;
• Sudden or unexplained weight gain;
• Swelling ankles or feet;
• Trouble breathing
This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.
You should not take Letairis if you are allergic to Ambrisentan or if you have any other allergies. Before you start taking this medication, talk to your doctor about your medical history and about all the medications you take including OTC and herbal medications. Letairis is controlled through a special program. If you a woman who may become pregnant, a program worker will call you every month to make sure you have gotten a pregnancy test. Women who are pregnant or may get pregnant should not handle the tablets or breathe the dust from this medication. It is recommended that at least two reliable forms of birth control be used while you are taking this medication and for one month after stopping the medication. It is unknown whether Ambrisentan passes into breast milk. Talk to your doctor before breast-feeding a baby.
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