Kynmobi (Apomorphine Hydrochloride) is used, as needed, to treat OFF episodes in adults with Parkinson’s disease. An OFF episode is when your Parkinson’s movement symptoms (e.g., tremor, slowness, stiffness and difficulty moving) are unexpectedly not controlled by your regular Parkinson’s medication. Kynmobi is for use with other drugs to treat Parkinson’s disease and does not replace the other drugs prescribed by your doctor to treat your Parkinson’s symptoms. Kynmobi belongs to a group of drugs called dopamine agonists. It seems to improve some of the chemical imbalance in the part of the brain affected by Parkinson’s disease. Kynmobi is for sublingual (under your tongue) use only. Kynmobi must be taken whole. Do not cut, chew or swallow Kynmobi. Your doctor may prescribe another medicine called an antiemetic (e.g., domperidone) to take while you are using Kynmobi. Antiemetic medicines may help to decrease the symptoms of nausea and vomiting that can happen with Kynmobi. Drink water and swallow excess water before taking the Kynmobi film.
Canadian Pharmacy King currently offers the brand Kynmobi (Apomorphine Hydrochloride) from Canada manufactured by Sunovion. Kynmobi is available in the strength of 10 mg, 15 mg, 20 mg, 25 mg, and 30 mg sublingual films.
The common side effects of Kynmobi may include nausea, vomiting, dizziness, dry mouth, fatigue, yawning, sleepiness, runny nose, increased sweating, headache, chills. Contact your doctor right away if you have any of the following symptoms:
• Dyskinesia: severe uncontrolled movements;
• Falls and injuries from falling;
• Low blood pressure: dizziness, fainting, light-headedness when rising to a sitting or standing position;
• Oral irritation: redness, swelling, infection, ulceration, pain or dryness of mouth, lips or tongue;
• Syncope: fainting when standing up
This is not a complete list of side effects and others may occur. Please call your doctor if you have any further concerns or questions.
Do not use Kynmobi if you: are allergic to apomorphine hydrochloride, sodium metabisulphite or to any of the ingredients in Kynmobi, are taking certain drugs used to treat nausea or vomiting such as ondansetron, have severe liver or kidney disease. To help avoid side effects, talk to your healthcare professional before you take Kynmobi about any health conditions including if you: have difficulty staying awake during the daytime, have undiagnosed changed patches of pigmented skin, including irritated moles, or moles in which you have noticed changes of skin cancer, have dizziness, have asthma, have a history of fibrosis, are allergic to any medicines containing sulfites, have severe uncontrolled involuntary movements, have liver or kidney problems, have any unusual eyes or eyesight conditions, have had a stroke or other brain problems, have any mental disorders or have hallucinations, drink alcohol, are pregnant or breast feeding. Kynmobi should not be used if you are pregnant or breast feeding. Kynmobi can cause problems with your heart rhythm called QTc prolongation. Tell your healthcare professional about all the medicines you take, including any drugs, vitamins, minerals, natural supplements or alternative medicines. The following may interact with Kynmobi: other medicines used to treat Parkinson’s disease, including levodopa, drugs used to treat nausea or vomiting, alcohol, drugs to lower your blood pressure such as antihypertensive drugs or vasodilators, drugs that can affect the levels of electrolytes (salts) in your body, certain drugs that have an effect on your heart rate, nitroglycerin, a drug used to improve blood flow.
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